c-MET 抗体 (AA 208-407)
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北京 101111
Quick Overview for c-MET 抗体 (AA 208-407) (ABIN8009297)
抗原
See all c-MET (MET) 抗体适用
宿主
克隆类型
标记
应用范围
质量等级
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抗原表位
- AA 208-407
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原理
- Anti-Met (c-Met) Antibody
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特异性
- No cross reactivity with other proteins.
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交叉反应 （详细）
- No cross-reactivity with other proteins
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预测反应
- Human Met shares 90%,91% amino acid (aa) sequences identity with mouse,rat Met,respectively.
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产品特性
- Anti-Met (c-Met) Antibody. Tested in WB applications. This antibody reacts with Human, Rat.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human Met recombinant protein (Position: D208-S407). Human Met shares 90% and 91% amino acid (aa) sequences identity with mouse and rat Met, respectively.
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亚型
- IgG
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anti-Met Proto-Oncogene (MET) (AA 25-150) antibody
MET 适用: 人, 小鼠 WB, ELISA, FACS, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Met Proto-Oncogene (MET) (C-Term) antibodyMET 适用: 人 WB, IHC, FACS, ICC, IP 宿主: 兔 Monoclonal BLR283L unconjugated Recombinant Antibody
anti-Met Proto-Oncogene (MET) (AA 743-932) antibodyMET 适用: 人, 猴 WB, ELISA, IHC, FACS, ICC 宿主: 小鼠 Monoclonal 5E9C4 unconjugated
anti-Met Proto-Oncogene (MET) (AA 1092-1379) antibodyMET 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Met Proto-Oncogene (MET) (AA 743-932) antibodyMET 适用: 人 ELISA, FACS, ICC 宿主: 小鼠 Monoclonal 5E9B7 unconjugated
anti-Met Proto-Oncogene (MET) antibodyMET 适用: 人 WB, ELISA, IHC, IF, FACS 宿主: 兔 Monoclonal 2D12 unconjugated Recombinant Antibody
anti-Met Proto-Oncogene (MET) (C-Term) antibodyMET 适用: 人 WB, IF, ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-Met Proto-Oncogene (MET) (Internal Region) antibodyMET 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Met Proto-Oncogene (MET) (AA 1-1390) antibodyMET 适用: 人 WB, PLA 宿主: 小鼠 Polyclonal unconjugated
anti-Met Proto-Oncogene (MET) (pTyr1234) antibodyMET 适用: 人, 小鼠, 大鼠 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
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应用备注
- Western blot, 0.1-0.5 μg/mL, Rat, Human
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains antibody formulated with stabilizing components, 0.9 mg NaCl, 0.2 mg Na2HPO4, and 0.05 mg Sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles. -
有效期
- 12 months
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- c-MET (MET) (Met Proto-Oncogene (MET))
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别名
- MET
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背景
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Background: c-Met, also called MET and hepatocyte growth factor receptor (HGFR), is a protein that in humans is encoded by the MET gene. It is mapped to 7q31.2. The protein possesses tyrosine kinase activity. MET is a membrane receptor that is essential for embryonic development and wound healing. It induces several biological responses that collectively give rise to a program known as invasive growth. MET is deregulated in many types of human malignancies, including cancers of kidney, liver, stomach, breast, and brain. Normally, only stem cells and progenitor cells express MET, which allows these cells to grow invasively in order to generate new tissues in an embryo or regenerate damaged tissues in an adult. However, cancer stem cells are thought to hijack the ability of normal stem cells to express MET, and thus become the cause of cancer persistence and spread to other sites in the body.
Gene Full Name: MET proto-oncogene, receptor tyrosine kinase
Sequence Similarities: Belongs to the protein kinase superfamily. Tyr protein kinase family.
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分子量
- 154 kDa
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基因ID
- 4233
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UniProt
- P08581
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途径
- RTK signaling, Carbohydrate Homeostasis, Synaptic Membrane, Signaling of Hepatocyte Growth Factor Receptor
抗原
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