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LEF1 抗体 (AA 14-274) (Cy3)

The 兔 多克隆 anti-LEF1 antibody is suitable to detect LEF1 in samples from 人, 小鼠 和 大鼠. It has been validated for FACS.
产品编号 ABIN8006868
发货至: 中国
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中国
北京 101111
No. 88 KeChuang 6th Street
Beijing Economic Technological Development Area
Room 801-803
4A Biotech Co.,Ltd.
Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for LEF1 抗体 (AA 14-274) (Cy3) (ABIN8006868)

抗原

See all LEF1 抗体
LEF1 (Lymphoid Enhancer-Binding Factor 1 (LEF1))

适用

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人, 小鼠, 大鼠

宿主

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克隆类型

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多克隆

标记

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This LEF1 antibody is conjugated to Cy3

应用范围

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Flow Cytometry (FACS)
  • 抗原表位

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    AA 14-274

    原理

    Anti-LEF1 Antibody Cy3 Conjugated

    交叉反应 (详细)

    No cross-reactivity with other proteins.

    纯化方法

    Immunogen affinity purified.

    免疫原

    E.coli-derived human LEF1 recombinant protein (Position: D14-H274).

    亚型

    IgG
  • 应用备注

    Flow Cytometry, 1-3 μg/1x106 cells

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

    有效期

    12 months
  • 抗原

    LEF1 (Lymphoid Enhancer-Binding Factor 1 (LEF1))

    别名

    LEF1

    背景

    Background: Lymphoid enhancer-binding factor 1 (LEF1) is a protein that in humans is encoded by the LEF1 gene. This gene encodes a transcription factor belonging to a family of proteins that share homology with the high mobility group protein-1. The protein encoded by this gene can bind to a functionally important site in the T-cell receptor-alpha enhancer, thereby conferring maximal enhancer activity. This transcription factor is involved in the Wnt signaling pathway, and it may function in hair cell differentiation and follicle morphogenesis. Mutations in this gene have been found in somatic sebaceous tumors. This gene has also been linked to other cancers, including androgen-independent prostate cancer. Alternative splicing results in multiple transcript variants.

    Gene Full Name: lymphoid enhancer binding factor 1

    基因ID

    51176

    UniProt

    Q9UJU2

    途径

    WNT signaling, Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Hormone Metabolic Process, Nuclear Hormone Receptor Binding, Chromatin Binding
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