IRAK4 抗体 (N-Term) (Cy3)
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北京 101111
Quick Overview for IRAK4 抗体 (N-Term) (Cy3) (ABIN8002993)
抗原
See all IRAK4 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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原理
- Anti-IRAK4 Antibody Cy3 Conjugated
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特异性
- No cross reactivity with other proteins.
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交叉反应 （详细）
- No cross-reactivity with other proteins
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预测反应
- identical to the related rat,mouse sequences.
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纯化方法
- Immunogen affinity purified.
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免疫原
- A synthetic peptide corresponding to a sequence at the N-terminus of human IRAK4, identical to the related rat and mouse sequences.
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亚型
- IgG
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anti-Interleukin-1 Receptor-Associated Kinase 4 (IRAK4) antibody
IRAK4 适用: 人, 小鼠, 猴 WB, ELISA, IHC, FACS 宿主: 小鼠 Monoclonal 2H9 unconjugated
anti-Interleukin-1 Receptor-Associated Kinase 4 (IRAK4) (AA 189-427) antibodyIRAK4 适用: 人 WB, ELISA, IHC (p), ICC, IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Interleukin-1 Receptor-Associated Kinase 4 (IRAK4) (AA 1-220) antibodyIRAK4 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Interleukin-1 Receptor-Associated Kinase 4 (IRAK4) (AA 5-36), (N-Term) antibodyIRAK4 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB2347 unconjugated
anti-Interleukin-1 Receptor-Associated Kinase 4 (IRAK4) (AA 1-130) antibodyIRAK4 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 2D3 unconjugated
anti-Interleukin-1 Receptor-Associated Kinase 4 (IRAK4) (N-Term) antibodyVerified IRAK4 适用: 人 WB, ELISA, IHC, FACS, IF 宿主: 山羊 Polyclonal unconjugated
anti-Interleukin-1 Receptor-Associated Kinase 4 (IRAK4) (pThr345) antibodyIRAK4 适用: 人, 小鼠, 大鼠, Cow, Pig, 犬 WB, IF (p), IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Interleukin-1 Receptor-Associated Kinase 4 (IRAK4) (AA 1-130) antibodyIRAK4 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 1D4 unconjugated
anti-Interleukin-1 Receptor-Associated Kinase 4 (IRAK4) (AA 25-52), (N-Term) antibodyIRAK4 适用: 人 WB 宿主: 兔 Polyclonal RB33094 unconjugated
anti-Interleukin-1 Receptor-Associated Kinase 4 (IRAK4) (pThr345) antibodyIRAK4 适用: 人, 小鼠 WB, ELISA, IF (p), IHC (p), IF (cc), IHC (fro) 宿主: 兔 Polyclonal unconjugated
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应用备注
- Flow Cytometry, 1-3 μg/1x106 cells
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.
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有效期
- 12 months
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- IRAK4 (Interleukin-1 Receptor-Associated Kinase 4 (IRAK4))
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别名
- IRAK4
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背景
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Background: IRAK-4 (interleukin-1 receptor-associated kinase 4), also called REN64, in the IRAK family, is a protein kinase involved in signaling innate immune responses from Toll-like receptors. It also supports signaling from T-cell receptors. Scott (2002) mapped the REN64/IRAK4 gene to chromosome 12 based on similarity between the REN64 sequence (GenBank AF155118) and a chromosome 12 clone (GenBank AC093012). Functional analysis by Li et al. (2002) determined that IRAK4, like IRAK1 and Pelle, has auto- and cross-phosphorylation kinase activity. Precipitation and binding analyses showed weak interaction between IRAK4 and IRAK1, but IRAK4 did not interact with other IRAK family members. Overexpressed IRAK4 interacted with MYD88 and TRAF6 and activated mitogen-activated protein kinase (MAPK) and nuclear factor kappa-B (NFKB) pathways.
Gene Full Name: interleukin 1 receptor associated kinase 4
Sequence Similarities: Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. Pelle subfamily.
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基因ID
- 51135
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UniProt
- Q9NWZ3
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途径
- NF-kappaB Signaling, TLR signaling, Activation of Innate immune Response, Toll-Like Receptors Cascades
抗原
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