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IRAK1 抗体 (AA 377-479) (Fluoro488)

The Fluoro488-conjugated 兔 多克隆 anti-IRAK1 antibody (ABIN8002906) specifically detects IRAK1 in WB, IHC, IF, FACS 和 ICC. The antibody is reactive with 人, 小鼠 和 大鼠 samples.
产品编号 ABIN8002906
发货至: 中国
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Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for IRAK1 抗体 (AA 377-479) (Fluoro488) (ABIN8002906)

抗原

See all IRAK1 抗体
IRAK1 (Interleukin-1 Receptor-Associated Kinase 1 (IRAK1))

适用

  • 166
  • 106
  • 57
  • 2
  • 1
  • 1
人, 小鼠, 大鼠

宿主

  • 193
  • 12
  • 2
兔

克隆类型

  • 183
  • 24
多克隆

标记

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This IRAK1 antibody is conjugated to Fluoro488

应用范围

  • 158
  • 85
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  • 23
  • 21
  • 15
  • 2
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Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Flow Cytometry (FACS), Immunocytochemistry (ICC)
  • 抗原表位

    • 34
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    • 1
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    • 1
    • 1
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    AA 377-479

    原理

    Anti-IRAK/IRAK1 Antibody Fluoro488 Conjugated

    特异性

    No cross reactivity with other proteins.

    交叉反应 (详细)

    No cross-reactivity with other proteins.

    纯化方法

    Immunogen affinity purified.

    免疫原

    E. coli-derived human IRAK recombinant protein (Position: M377-D479).

    亚型

    IgG
  • 应用备注

    Western blot, 0.25-0.5 μg/mL, Human, Mouse, Rat Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL, Human Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human

    说明

    Applications are recommended based on the unconjugated antibody.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

    有效期

    12 months
  • 抗原

    IRAK1 (Interleukin-1 Receptor-Associated Kinase 1 (IRAK1))

    别名

    IRAK1

    背景

    Background: Interleukin-1 receptor-associated kinase 1, also called IRAK1, is an enzyme that in humans is encoded by the IRAK1 gene. By radiation hybrid analysis, this gene is mapped to chromosome Xq28. Serine/threonine-protein kinase plays a critical role in initiating innate immune response against foreign pathogens. This gene involved in Toll-like receptor (TLR) and IL-1R signaling pathways. This gene encodes the interleukin-1 receptor-associated kinase 1, one of two putative serine/threonine kinases that become associated with the interleukin-1 receptor (IL1R) upon stimulation. This gene is partially responsible for IL1-induced upregulation of the transcription factor NF-kappa B.

    Gene Full Name: interleukin 1 receptor associated kinase 1

    基因ID

    3654

    UniProt

    P51617

    途径

    NF-kappaB Signaling, TLR signaling, Neurotrophin Signaling Pathway, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Toll-Like Receptors Cascades
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