TP53BP1 抗体 (AA 501-600)
Quick Overview for TP53BP1 抗体 (AA 501-600) (ABIN749933)
抗原
See all TP53BP1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 501-600
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交叉反应
- 大鼠
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预测反应
- Human,Mouse,Dog,Rabbit
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纯化方法
- Purified by Protein A.
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免疫原
- KLH conjugated synthetic peptide derived from human p53BP1
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亚型
- IgG
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应用备注
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ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500 -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 μg/μL
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缓冲液
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
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有效期
- 12 months
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- TP53BP1 (Tumor Protein P53 Binding Protein 1 (TP53BP1))
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别名
- p53BP1
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背景
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Synonyms: 53 BP1, FLJ41424, MGC138366, p202, p53 binding protein 1, p53 BP1, p53BP1, TP53 BP1, TP53BP1, Tumor protein 53 binding protein 1, Tumor protein p53 binding protein 1, Tumor suppressor p53 binding protein 1, TP53B_HUMAN, tumor protein 53-binding protein, 1.
Background: p53 binding protein 1 (53BP1) plays a critical role in tumor suppression and is a putative substrate of ATM kinase. Upon DNA damage, it is phosphorylated and relocalizes to the presumptive sites of damage, p53 binding protein 1 (53BP1) plays a critical role in tumor suppression and is a putative substrate of ATM kinase. Upon DNA damage, it is phosphorylated and relocalizes to the presumptive sites of damage, specifically, double strand breaks. This also suggests a role in DNA repair, maintaining genomic stability.
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基因ID
- 7158
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途径
- DNA Damage Repair
抗原
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