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TP53BP1 抗体 (N-Term)

KO Validated TP53BP1 适用: 人 WB, IF, ICC, IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2855433
发货至: 中国
  • 抗原 See all TP53BP1 抗体
    TP53BP1 (Tumor Protein P53 Binding Protein 1 (TP53BP1))
    抗原表位
    • 21
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    N-Term
    适用
    • 91
    • 50
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    • 6
    • 4
    • 4
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    • 1
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    • 1
    宿主
    • 95
    • 8
    • 2
    • 1
    克隆类型
    • 88
    • 18
    多克隆
    标记
    • 57
    • 5
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    • 5
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    • 2
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    This TP53BP1 antibody is un-conjugated
    应用范围
    • 42
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    • 18
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    • 13
    • 11
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    Western Blotting (WB), Immunofluorescence (IF), Immunocytochemistry (ICC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
    交叉反应
    人, 小鼠
    产品特性
    Rabbit Polyclonal antibody to 53BP1 (tumor protein p53 binding protein 1)
    53BP1 antibody [N1], N-term
    纯化方法
    Purified by antigen-affinity chromatography.
    质量等级
    KO Validated
    免疫原
    Recombinant protein encompassing a sequence within the N-terminus region of human 53BP1. The exact sequence is proprietary.
    亚型
    IgG
    Top Product
    Discover our top product TP53BP1 Primary Antibody
  • 应用备注
    WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
    说明

    Positive Control: 293T , HeLa , Neuro 2A , C8D30 , NIH-3T3

    Validation: KO/KD

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    0.1M Tris-Glycine ( pH 7), 10 % Glycerol, 0.01 % Thimerosal
    储存液
    Thimerosal (Merthiolate)
    注意事项
    This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • 抗原
    TP53BP1 (Tumor Protein P53 Binding Protein 1 (TP53BP1))
    别名
    tumor protein p53 binding protein 1 (TP53BP1 产品)
    别名
    TP53BP1 antibody, MGC160112 antibody, 53BP1 antibody, Tp53bp1 antibody, m53BP1 antibody, p202 antibody, Trp53bp1 antibody, tumor protein p53 binding protein 1 antibody, tumor suppressor p53-binding protein 1 antibody, tumor protein p53 binding protein 1 (predicted), 5 prime antibody, transformation related protein 53 binding protein 1 antibody, TP53BP1 antibody, tp53bp1 antibody, LOC100550605 antibody, Trp53bp1 antibody, Tp53bp1 antibody
    背景
    May have a role in checkpoint signaling during mitosis (By similarity). Enhances TP53-mediated transcriptional activation. Plays a role in the response to DNA damage.

    Cellular Localization: Nucleus , Kinetochore
    分子量
    214 kDa
    基因ID
    7158
    UniProt
    Q12888
    途径
    DNA Damage Repair
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