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GTPase NRas 抗体 (C-Term) (Fluoro550)

The 兔 多克隆 anti-GTPase NRas antibody is suitable to detect GTPase NRas in samples from 人, 大鼠 和 小鼠. It has been validated for FACS.
产品编号 ABIN7995595
发货至: 中国
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北京 101111
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Beijing Economic Technological Development Area
Room 801-803
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Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for GTPase NRas 抗体 (C-Term) (Fluoro550) (ABIN7995595)

抗原

See all GTPase NRas (NRAS) 抗体
GTPase NRas (NRAS)

适用

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人, 大鼠, 小鼠

宿主

  • 58
  • 13
  • 1

克隆类型

  • 48
  • 24
多克隆

标记

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This GTPase NRas antibody is conjugated to Fluoro550

应用范围

  • 53
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  • 15
  • 9
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  • 4
  • 2
  • 2
  • 1
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Flow Cytometry (FACS)
  • 抗原表位

    • 15
    • 6
    • 6
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term

    原理

    Anti-NRAS Antibody Fluoro550 Conjugated

    交叉反应 (详细)

    No cross-reactivity with other proteins

    预测反应

    Human NRAS shares 100% amino acid (aa) sequence identity with both mouse,rat NRAS.

    纯化方法

    Immunogen affinity purified.

    免疫原

    A synthetic peptide corresponding to a sequence at the C-terminus of human NRAS. Human NRAS shares 100% amino acid (aa) sequence identity with both mouse and rat NRAS.

    亚型

    IgG
  • 应用备注

    Flow Cytometry, Optimal dilutions should be determined by end users.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

    有效期

    12 months
  • 抗原

    GTPase NRas (NRAS)

    别名

    NRAS

    背景

    Background: This is an N-ras oncogene encoding a membrane protein that shuttles between the Golgi apparatus and the plasma membrane. This shuttling is regulated through palmitoylation and depalmitoylation by the ZDHHC9-GOLGA7 complex. The encoded protein, which has intrinsic GTPase activity, is activated by a guanine nucleotide-exchange factor and inactivated by a GTPase activating protein. Mutations in this gene have been associated with somatic rectal cancer, follicular thyroid cancer, autoimmune lymphoproliferative syndrome, Noonan syndrome, and juvenile myelomonocytic leukemia.

    Gene Full Name: NRAS proto-oncogene, GTPase

    基因ID

    4893

    UniProt

    P01111

    途径

    p53 Pathway, MAPK Pathway, RTK signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Hepatitis C, Regulation of long-term Neuronal Synaptic Plasticity, VEGF Signaling
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