IRS1 抗体 (pSer307) (Biotin)
Quick Overview for IRS1 抗体 (pSer307) (Biotin) (ABIN749875)
抗原
See all IRS1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- pSer307
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特异性
- This phosphorylation site is homologous to Ser302 in Mouse and Rat.
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交叉反应
- 山羊, 人, 小鼠, 大鼠
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预测反应
- Dog,Cow,Pig,Horse,Rabbit
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纯化方法
- Purified by Protein A.
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免疫原
- KLH conjugated synthetic phosphopeptide derived from human IRS1 around the phosphorylation site of Ser307 [TE(p-S)IT]
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亚型
- IgG
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应用备注
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WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500 -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 μg/μL
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缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C for 12 months.
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有效期
- 12 months
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- IRS1 (Insulin Receptor Substrate 1 (IRS1))
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别名
- IRS-1
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背景
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Synonyms: HIRS-1, Insulin receptor substrate 1, IRS-1, IRS1
Background: May mediate the control of various cellular processes by insulin. When phosphorylated by the insulin receptor binds specifically to various cellular proteins containing SH2 domains such as phosphatidylinositol 3-kinase p85 subunit or GRB2. Activates phosphatidylinositol 3-kinase when bound to the regulatory p85 subunit (By similarity).
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基因ID
- 3667
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UniProt
- P35568
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途径
- Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Positive Regulation of Peptide Hormone Secretion, Hormone Transport, Negative Regulation of Hormone Secretion, Response to Growth Hormone Stimulus, Carbohydrate Homeostasis, Regulation of Carbohydrate Metabolic Process
抗原
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