Connexin 43/GJA1 抗体 (C-Term)
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北京 101111
Quick Overview for Connexin 43/GJA1 抗体 (C-Term) (ABIN7992639)
抗原
See all Connexin 43/GJA1 (GJA1) 抗体适用
宿主
克隆类型
标记
应用范围
质量等级
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抗原表位
- C-Term
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原理
- Anti-Connexin 43/GJA1 Antibody
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特异性
- No cross reactivity with other proteins.
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交叉反应 （详细）
- No cross-reactivity with other proteins
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预测反应
- identical to the related rat,mouse sequences.
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产品特性
- Anti-Connexin 43/GJA1 Antibody-1. Tested in IHC, WB applications. This antibody reacts with Human, Mouse, Rat.
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纯化方法
- Immunogen affinity purified.
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免疫原
- A synthetic peptide corresponding to a sequence at the C-terminus of human Connexin 43, identical to the related rat and mouse sequences.
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亚型
- IgG
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anti-Gap Junction Protein, alpha 1, 43kDa (GJA1) (C-Term) antibody
GJA1 适用: 人, 小鼠, 大鼠, 犬, 猴, Cow, 小鸡, 兔, Pig, 豚鼠, 马, 绵羊, Hamster, 山羊, Avian, Cat, 驴 WB, IF, IHC (p), IHC (fro) 宿主: 山羊 Polyclonal unconjugated
anti-Gap Junction Protein, alpha 1, 43kDa (GJA1) (pSer368) antibodyGJA1 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Gap Junction Protein, alpha 1, 43kDa (GJA1) (AA 310-390) antibodyGJA1 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Gap Junction Protein, alpha 1, 43kDa (GJA1) (AA 211-260) antibodyGJA1 适用: 人, 小鼠, 大鼠, 犬 WB, ELISA, IHC (p), IF (p), FACS, IF (cc), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Gap Junction Protein, alpha 1, 43kDa (GJA1) (AA 244-382) antibodyGJA1 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Gap Junction Protein, alpha 1, 43kDa (GJA1) (AA 233-382) antibodyGJA1 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Gap Junction Protein, alpha 1, 43kDa (GJA1) (AA 331-345), (C-Term), (Intracellular) antibodyGJA1 适用: 人 WB, IHC, IF 宿主: 豚鼠 Polyclonal unconjugated
anti-Gap Junction Protein, alpha 1, 43kDa (GJA1) (AA 351-367) antibodyGJA1 适用: 人, 小鼠, 大鼠 WB, IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Gap Junction Protein, alpha 1, 43kDa (GJA1) (AA 107-138) antibodyGJA1 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Gap Junction Protein, alpha 1, 43kDa (GJA1) (C-Term) antibodyGJA1 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
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应用备注
- Immunohistochemistry (Frozen Section), 0.5-1 μg/mLImmunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mLWestern blot, 0.1-0.5 μg/mL
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains antibody formulated with stabilizing components, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.01 mg Thimerosal, 0.01 mg Sodium azide.
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储存液
- Sodium azide, Thimerosal (Merthiolate)
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注意事项
- This product contains Thimerosal (Merthiolate) and Sodium azide: POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles. -
有效期
- 12 months
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- Connexin 43/GJA1 (GJA1) (Gap Junction Protein, alpha 1, 43kDa (GJA1))
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别名
- GJA1
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背景
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Background: Connexins 43 (Cx43), also called GAP Junction Protein, alpha-1 (GJA1). Connexin 43 is a member of the connexin gene family which abundantly expressed in the heart and liver and was mapped to 6q21-q23.2. Connexin43, the major protein of gap junctions in the heart, is targeted by several protein kinases that regulate myocardial cell-cell coupling. Mutations in the connexin43 gap-junction gene, which lead to abnormally regulated cell-cell communication, are associated with visceroatrial heterotaxia. Cx43 must also play a critical role in the physiology of hearing, presumably by participating in the recycling of potassium to the cochlear endolymph.
Gene Full Name: gap junction protein alpha 1
Sequence Similarities: Belongs to the connexin family. Alpha-type (group II) subfamily.
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分子量
- 43 kDa
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基因ID
- 2697
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UniProt
- P17302
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途径
- MAPK Pathway, Myometrial Relaxation and Contraction, Cell-Cell Junction Organization
抗原
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