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GBL 抗体 (AA 11-326) (Biotin)

The 兔 多克隆 anti-GBL antibody is suitable to detect GBL in samples from 人, 小鼠 和 大鼠. It has been validated for WB, ELISA 和 IHC.
产品编号 ABIN7992088
发货至: 中国
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Quick Overview for GBL 抗体 (AA 11-326) (Biotin) (ABIN7992088)

抗原

See all GBL 抗体
GBL (G protein beta subunit-like (GBL))

适用

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人, 小鼠, 大鼠

宿主

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克隆类型

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多克隆

标记

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This GBL antibody is conjugated to Biotin

应用范围

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Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
  • 抗原表位

    • 15
    • 11
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    AA 11-326

    原理

    Anti-MLST8 Antibody Biotin Conjugated

    交叉反应 (详细)

    No cross-reactivity with other proteins.

    纯化方法

    Immunogen affinity purified.

    免疫原

    E.coli-derived human MLST8 recombinant protein (Position: D11-G326).

    亚型

    IgG
  • 应用备注

    Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.

    有效期

    12 months
  • 抗原

    GBL (G protein beta subunit-like (GBL))

    别名

    MLST8

    背景

    Background: Target of rapamycin complex subunit LST8, also known as mammalian lethal with SEC13 protein 8 (mLST8) or TORC subunit LST8 or G protein beta subunit-like (GβL or Gable), is a protein that in humans is encoded by the MLST8 (MTOR associated protein, LST8 homolog) gene. mTOR is a serine/threonine kinase that acts in two distinct complexes, mTORC1 and mTORC2, and is dysregulated in many diseases including cancer. mLST8 is a shared component of both mTORC1 and mTORC2. Mammalian lethal with SEC13 protein 8 (mLST8), is an indispensable protein subunit of mammalian target of rapamycin (mTOR) signaling pathway that interacts with the kinase domain of mTOR protein, thereby stabilizing its active site.

    Gene Full Name: MTOR associated protein MLST8

    基因ID

    64223

    UniProt

    Q9BVC4

    途径

    PI3K-Akt Signaling, RTK signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Regulation of Actin Filament Polymerization, Autophagy, CXCR4-mediated Signaling Events, BCR Signaling, Warburg Effect
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