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FGFR4 抗体 (AA 22-206) (Cy3)

This 兔 多克隆 antibody specifically detects FGFR4 in FACS. It exhibits reactivity toward 人.
产品编号 ABIN7990776
发货至: 中国
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Quick Overview for FGFR4 抗体 (AA 22-206) (Cy3) (ABIN7990776)

抗原

See all FGFR4 抗体
FGFR4 (Fibroblast Growth Factor Receptor 4 (FGFR4))

适用

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宿主

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克隆类型

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多克隆

标记

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This FGFR4 antibody is conjugated to Cy3

应用范围

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Flow Cytometry (FACS)
  • 抗原表位

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    AA 22-206

    原理

    Anti-FGFR4 Antibody Cy3 Conjugated

    特异性

    No cross reactivity with other proteins.

    交叉反应 (详细)

    No cross-reactivity with other proteins

    预测反应

    Human FGFR4 shares 86%,84% amino acid (aa) sequences identity with mouse,rat FGFR4,respectively.

    纯化方法

    Immunogen affinity purified.

    免疫原

    E.coli-derived human FGFR4 recombinant protein (Position: L22-H206). Human FGFR4 shares 86% and 84% amino acid (aa) sequences identity with mouse and rat FGFR4, respectively.

    亚型

    IgG
  • 应用备注

    Flow Cytometry, 1-3 μg/1x106 cells

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

    有效期

    12 months
  • 抗原

    FGFR4 (Fibroblast Growth Factor Receptor 4 (FGFR4))

    别名

    FGFR4

    背景

    Background: FGFR4 (Fibroblast growth factor receptor 4), also known as CD334, is a protein that in humans is encoded by the FGFR4 gene. It is mapped to 5q35.2. The protein encoded by this gene is a member of the fibroblast growth factor receptor family, where amino acid sequence is highly conserved between members and throughout evolution. The extracellular portion of the protein interacts with fibroblast growth factors, setting in motion a cascade of downstream signals, ultimately influencing mitogenesis and differentiation. It is overexpressed in gynecological tumor samples, suggesting a role in breast and ovarian tumorigenesis.

    Gene Full Name: fibroblast growth factor receptor 4

    Sequence Similarities: Belongs to the protein kinase superfamily. Tyr protein kinase family. Fibroblast growth factor receptor subfamily.

    基因ID

    2264

    UniProt

    P22455

    途径

    RTK signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Carbohydrate Homeostasis, Growth Factor Binding
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