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ERK1 抗体 (AA 251-358)

Name: ERK1 抗体 (AA 251-358)
SKU: ABIN748373
Availability: OutOfStock

This anti-ERK1 antibody is a 兔多克隆 antibody detecting ERK1 in WB, ELISA, IHC (p), IF (p), IF (cc) 和 IHC (fro). Suitable for 人, 小鼠, 大鼠, 小鸡和兔. This Primary Antibody has been cited in 18+ publications.

A549 cell lysates probed with Rabbit Anti-ERK1 + 2 Polyclonal Antibody, Unconjugated at 1:500 for 90 min at 37˚C. (ERK1 抗体 (AA 251-358))

Formalin-fixed and paraffin embedded human lung carcinoma labeled with Rabbit Anti ERK1/2(p44/42 MAPK) Polyclonal Antibody, Unconjugated (ABIN748373) at 1:200 followed by conjugation to the secondary antibody and DAB staining (ERK1 抗体 (AA 251-358))

IHC

Lane 1: mouse heart lysates Lane 2: mouse brain lysates probed with Anti ERK1/2(p42/p42 MAPK) Polyclonal Antibody, Unconjugated (ABIN748373) at 1:200 in 4 °C. (ERK1 抗体 (AA 251-358))

SDS

3 images

(18 references)

产品编号 ABIN748373

发货至: 中国

Quick Overview for ERK1 抗体 (AA 251-358) (ABIN748373)

抗原

See all ERK1 (MAPK3) 抗体

ERK1 (MAPK3) (Mitogen-Activated Protein Kinase 3 (MAPK3))

适用

人, 小鼠, 大鼠, 小鸡, 兔

宿主

兔

克隆类型

多克隆

标记

This ERK1 antibody is un-conjugated

应用范围

Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Discover our top product MAPK3 Primary Antibody

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AA 251-358

交叉反应

小鸡, 人, 小鼠, 兔, 大鼠

预测反应

Dog,Cow,Pig,Horse

纯化方法

Purified by Protein A.

免疫原

KLH conjugated synthetic peptide derived from mouse ERK2

亚型

IgG
anti-Mitogen-Activated Protein Kinase 3 (MAPK3) (AA 101-200) antibody
MAPK3 适用: 人, 小鼠, 大鼠, 小鸡 WB, ELISA, IHC (p), IF (p), IF (cc), FACS, IHC (fro) 宿主: 兔 Polyclonal unconjugated

anti-Mitogen-Activated Protein Kinase 3 (MAPK3) (pTyr204) antibody
MAPK3 适用: 人 WB, IHC, IF, IP 宿主: 兔 Polyclonal unconjugated

anti-Mitogen-Activated Protein Kinase 3 (MAPK3) (AA 1-100) antibody
MAPK3 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated

anti-Mitogen-Activated Protein Kinase 3 (MAPK3) antibody
MAPK3 适用: 大鼠 WB, IHC, IF, ICC, FACS 宿主: 兔 Polyclonal unconjugated

anti-Mitogen-Activated Protein Kinase 3 (MAPK3) antibody
MAPK3 适用: 人, 小鼠, 大鼠, 猴 WB, IHC, ELISA, ICC, FACS 宿主: 小鼠 Monoclonal 1E5 unconjugated

anti-Mitogen-Activated Protein Kinase 3 (MAPK3) (AA 75-312) antibody
MAPK3 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

anti-Mitogen-Activated Protein Kinase 3 (MAPK3) (AA 75-312) antibody
MAPK3 适用: 人 WB, IHC, IP, ICC 宿主: 小鼠 Monoclonal C3 unconjugated

anti-Mitogen-Activated Protein Kinase 3 (MAPK3) (N-Term) antibody
Verified MAPK3 适用: 人 WB, ELISA, IF, FACS 宿主: 山羊 Polyclonal unconjugated

anti-Mitogen-Activated Protein Kinase 3 (MAPK3) (pThr185), (pThr202), (pTyr187), (pTyr204) antibody
MAPK3 适用: 人, 小鼠, 大鼠 IHC 宿主: 兔 Polyclonal unconjugated

anti-Mitogen-Activated Protein Kinase 3 (MAPK3) (AA 279-379) antibody
MAPK3 适用: 人 WB, ELISA, IF, IHC (p), IP 宿主: 小鼠 Monoclonal 3C9 unconjugated

应用备注

WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

限制

仅限研究用
状态

Liquid

浓度

1 μg/μL

缓冲液

0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

储存液

ProClin

注意事项

This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

储存条件

4 °C,-20 °C

储存方法

Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

有效期

12 months
Zhang, Liu, Wang, Xie, Sheng, Zhang, Yuan, Han, Weng: "Seasonal Expression of Oxytocin and Oxytocin Receptor in the Scented Gland of Male Muskrat (Ondatra zibethicus)." in: Scientific reports, Vol. 7, Issue 1, pp. 16627, (2018) (PubMed).

Zhao, Han, Hong, Sun: "Adipose differentiation‑related protein knockdown inhibits vascular smooth muscle cell proliferation and migration and attenuates neointima formation." in: Molecular medicine reports, Vol. 16, Issue 3, pp. 3079-3086, (2018) (PubMed).

Liu, Zhang, Han, Wang, Liu, Zhang, Zhou, Xiang: "Inhibition of BTK protects lungs from trauma-hemorrhagic shock-induced injury in rats." in: Molecular medicine reports, Vol. 16, Issue 1, pp. 192-200, (2017) (PubMed).

Xu, Deng, Wang, Chen, Li, Fan: "RKTG overexpression inhibits proliferation and induces apoptosis of human leukemia cells via suppression of the ERK and PI3K/AKT signaling pathways." in: Oncology letters, Vol. 14, Issue 1, pp. 965-970, (2017) (PubMed).

Zheng, Wang, Zou, Jing, Yang, Li, Wang: "Ginsenoside Rb1 improves cardiac function and remodeling in heart failure." in: Experimental animals, Vol. 66, Issue 3, pp. 217-228, (2017) (PubMed).

Li, Wang, Zhou, Zhang, Le, He: "Downregulation of BRAF-activated non-coding RNA suppresses the proliferation, migration and invasion, and induces apoptosis of hepatocellular carcinoma cells." in: Oncology letters, Vol. 14, Issue 4, pp. 4751-4757, (2017) (PubMed).

Cong, Chen: "Neuroprotective Effect of Ginsenoside Rd in Spinal Cord Injury Rats." in: Basic & clinical pharmacology & toxicology, Vol. 119, Issue 2, pp. 193-201, (2016) (PubMed).

Yu, Shi, Qi, Zhao, Gao, Li: "Gypenoside Protects Cardiomyocytes against Ischemia-Reperfusion Injury via the Inhibition of Mitogen-Activated Protein Kinase Mediated Nuclear Factor Kappa B Pathway In Vitro and In Vivo." in: Frontiers in pharmacology, Vol. 7, pp. 148, (2016) (PubMed).

Zhao, Xue, Guo, Sun, Liu, Wang: "Inhibition of endocan attenuates monocrotaline-induced connective tissue disease related pulmonary arterial hypertension." in: International immunopharmacology, Vol. 42, pp. 115-121, (2016) (PubMed).

Li, Zheng, Su, Wang, Ling, Zou, Zhou: "Activation of the Extracellular Signal-Regulated Kinase Signaling Is Critical for Human Umbilical Cord Mesenchymal Stem Cell Osteogenic Differentiation." in: BioMed research international, Vol. 2016, pp. 3764372, (2016) (PubMed).

Chen, Shi, Li, Deng, Zhang: "Downregulation of MACC1 expression enhances cisplatin sensitivity in SKOV-3/DDP cells." in: Genetics and molecular research : GMR, Vol. 14, Issue 4, pp. 17134-44, (2016) (PubMed).

Wang, Zhao, Guo, Zhang, Pei: "Picroside II Inhibits Neuronal Apoptosis and Improves the Morphology and Structure of Brain Tissue following Cerebral Ischemic Injury in Rats." in: PLoS ONE, Vol. 10, Issue 4, pp. e0124099, (2015) (PubMed).

Wang, Zhai, Guo, Pei, Zhang: "Picroside II has a neuroprotective effect by inhibiting ERK1/2 activation after cerebral ischemic injury in rats." in: Clinical and experimental pharmacology & physiology, (2015) (PubMed).

Chen, Bao, Chen, Burton, Gong, Gu, Mi, Bao: "Mycobacterium tuberculosis PE25/PPE41 protein complex induces activation and maturation of dendritic cells and drives Th2-biased immune responses." in: Medical microbiology and immunology, (2015) (PubMed).

Zhao, Liu, Liu, Han, Zhao: "Betulin attenuates lung and liver injuries in sepsis." in: International immunopharmacology, Vol. 30, pp. 50-6, (2015) (PubMed).

An, Dang, Shi, Ye, Wu: ""Qufeng Tongluo" acupuncture prevents the progression of glomerulonephritis by decreasing renal sympathetic nerve activity." in: Journal of ethnopharmacology, Vol. 155, Issue 1, pp. 277-84, (2014) (PubMed).

Xu, Guo, Gao, Shi, He, Gao, Zhang: "Acyldepsipeptides inhibit the growth of renal cancer cells through G1 phase cell cycle arrest." in: Biochemical and biophysical research communications, Vol. 438, Issue 3, pp. 468-72, (2013) (PubMed).
抗原

ERK1 (MAPK3) (Mitogen-Activated Protein Kinase 3 (MAPK3))

别名

ERK1

背景

Synonyms: ERK, Erk2, MAPK2, PRKM2, Prkm1, C78273, p41mapk, p42mapk, AA47128, AU18647, 93612K14Rik, Mitogen-activated protein kinase 1, MAP kinase 1, MAPK 1, ERT1, Extracellular signal-regulated kinase 2, ERK-2, MAP kinase isoform p42, p42-MAPK, Mitogen-activated protein kinase 2, MAP kinase 2, MAPK 2, Mapk1, Mapk, ERK1/2
Background: The protein encoded by this gene is a member of the MAPkinase family. MAP kinases, also known as extracellularsignal-regulated kinases (ERKs), act in a signaling cascade thatregulates various cellular processes such as proliferation,differentiation, and cell cycle progression in response to avariety of extracellular signals. This kinase is activated byupstream kinases, resulting in its translocation to the nucleuswhere it phosphorylates nuclear targets. Alternatively splicedtranscript variants encoding different protein isoforms have beendescribed. [provided by RefSeq, Jul 2008].

基因ID

26413

UniProt

P63085

途径

MAPK Pathway, RTK signaling, Interferon-gamma Pathway, Fc-epsilon Receptor Signaling Pathway, Neurotrophin Signaling Pathway, Response to Growth Hormone Stimulus, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Hepatitis C, Protein targeting to Nucleus, Toll-Like Receptors Cascades, Signaling Events mediated by VEGFR1 and VEGFR2, Signaling of Hepatocyte Growth Factor Receptor, VEGFR1 Specific Signals, S100 Proteins