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JNK 抗体 (AA 151-250)

Name: JNK 抗体 (AA 151-250)
SKU: ABIN747713
Availability: OutOfStock

This anti-JNK antibody is a 兔多克隆 antibody detecting JNK in WB, ELISA, IHC (p), FACS, IF (cc), IF (p) 和 IHC (fro). Suitable for 人, 小鼠, 大鼠, 小鸡和 Pig. This Primary Antibody has been cited in 2+ publications.

Formalin-fixed and paraffin embedded human lung carcinoma labeled with Rabbit Anti-JNK1/2/3 Polyclonal Antibody, Unconjugated (ABIN747713) at 1:200 followed by conjugation to the secondary antibody and DAB staining (JNK 抗体 (AA 151-250))

IHC

Formalin-fixed and paraffin embedded rat brain labeled with Rabbit Anti JNK1/2/3 Polyclonal Antibody, Unconjugated (ABIN747713) at 1:200 followed by conjugation to the secondary antibody and DAB staining (JNK 抗体 (AA 151-250))

IHC

Paraformaldehyde-fixed, paraffin embedded Mouse brain Antigen retrieval by boiling in sodium citrate buffer (pH6. (JNK 抗体 (AA 151-250))

IHC (p)

3 images

(2 references)

产品编号 ABIN747713

发货至: 中国

Quick Overview for JNK 抗体 (AA 151-250) (ABIN747713)

抗原

See all JNK (MAPK8) 抗体

JNK (MAPK8) (Mitogen-Activated Protein Kinase 8 (MAPK8))

适用

人, 小鼠, 大鼠, 小鸡, Pig

宿主

兔

克隆类型

多克隆

标记

This JNK antibody is un-conjugated

应用范围

Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Discover our top product MAPK8 Primary Antibody

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AA 151-250

交叉反应

小鸡, 人, 小鼠, Pig, 大鼠

预测反应

Dog,Cow

纯化方法

Purified by Protein A.

免疫原

KLH conjugated synthetic peptide derived from mouse JNK1/2/3

亚型

IgG
anti-Mitogen-Activated Protein Kinase 8 (MAPK8) (AA 245-345) antibody
MAPK8 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated

anti-Mitogen-Activated Protein Kinase 8 (MAPK8) (pThr183), (pTyr185) antibody
MAPK8 适用: 人, 小鼠, 大鼠, 犬, 兔 WB, ELISA, IHC (p), FACS, IF (cc), IF (p), ICC, IHC (fro) 宿主: 兔 Polyclonal unconjugated

anti-Mitogen-Activated Protein Kinase 8 (MAPK8) (AA 138-370) antibody
MAPK8 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

anti-Mitogen-Activated Protein Kinase 8 (MAPK8) (AA 1-384) antibody
MAPK8 适用: 人 WB, ELISA, IF, PLA, RNAi 宿主: 小鼠 Monoclonal 2F11 unconjugated

anti-Mitogen-Activated Protein Kinase 8 (MAPK8) antibody
MAPK8 适用: 人, 小鼠, 大鼠, Pig WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated

anti-Mitogen-Activated Protein Kinase 8 (MAPK8) (AA 201-300) antibody
MAPK8 适用: 人, 小鼠, 大鼠, 小鸡, 犬 WB, ELISA, IHC (p), FACS, IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated

anti-Mitogen-Activated Protein Kinase 8 (MAPK8) (AA 145-419) antibody
MAPK8 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated

anti-Mitogen-Activated Protein Kinase 8 (MAPK8) (AA 1-427) antibody
MAPK8 适用: 人 WB, IF, PLA 宿主: 兔 Polyclonal unconjugated

anti-Mitogen-Activated Protein Kinase 8 (MAPK8) (AA 318-427) antibody
MAPK8 适用: 人 WB, ELISA, IF, IP 宿主: 小鼠 Monoclonal 4A11 unconjugated

anti-Mitogen-Activated Protein Kinase 8 (MAPK8) (AA 138-382) antibody
MAPK8 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

应用备注

WB 1:300-5000
ELISA 1:500-1000
FCM 1:20-100
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

限制

仅限研究用
状态

Liquid

浓度

1 μg/μL

缓冲液

0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

储存液

ProClin

注意事项

This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

储存条件

4 °C,-20 °C

储存方法

Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

有效期

12 months
Wang, Fan, Chu, Zhang, Rahman, Jiang, Chen, Zhu, Feng, Li, Wu: "Deoxynivalenol induces toxicity and apoptosis in piglet hippocampal nerve cells via the MAPK signaling pathway." in: Toxicon : official journal of the International Society on Toxinology, Vol. 155, pp. 1-8, (2018) (PubMed).

Li, Qiu, Lin, He, Hua, Yuan, Liu, Wei: "c-Jun N-terminal kinase is upregulated in patients with hypospadias." in: Urology, Vol. 81, Issue 1, pp. 178-83, (2012) (PubMed).
抗原

JNK (MAPK8) (Mitogen-Activated Protein Kinase 8 (MAPK8))

别名

JNK1+2+3

背景

Synonyms: JNK3, Serk2, JNK3B1, JNK3B2, p493F12, p54bSAPK, SAPK(beta), C238H4Rik, JNK, JNK1, Prkm8, SAPK1, AI849689, JNK2, Prkm9, AI85183, p54aSAPK, Mitogen-activated protein kinase 1, MAP kinase 1, MAPK 1, MAP kinase p49 3F12, Stress-activated protein kinase JNK3, c-Jun N-terminal kinase 3, Mapk1, Prkm1
Background: Serine/threonine-protein kinase involved in various processes such as neuronal proliferation, differentiation, migration and programmed cell death. Extracellular stimuli such as proinflammatory cytokines or physical stress stimulate the stress-activated protein kinase/c-Jun N-terminal kinase (SAP/JNK) signaling pathway. In this cascade, two dual specificity kinases MAP2K4/MKK4 and MAP2K7/MKK7 phosphorylate and activate MAPK1/JNK3. In turn, MAPK1/JNK3 phosphorylates a number of transcription factors, primarily components of AP-1 such as JUN and ATF2 and thus regulates AP-1 transcriptional activity. Plays regulatory roles in the signaling pathways during neuronal apoptosis. Phosphorylates the neuronal microtubule regulator STMN2. Acts in the regulation of the beta-amyloid precursor protein/APP signaling during neuronal differentiation by phosphorylating APP. Participates also in neurite growth in spiral ganglion neurons.

UniProt

Q61831

途径

MAPK Pathway, WNT signaling, TLR signaling, Fc-epsilon Receptor Signaling Pathway, Neurotrophin Signaling Pathway, Activation of Innate immune Response, Hepatitis C, Toll-Like Receptors Cascades, Signaling of Hepatocyte Growth Factor Receptor, S100 Proteins