BARD1 抗体 (AA 709-758) (Fluoro488)
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北京 101111
Quick Overview for BARD1 抗体 (AA 709-758) (Fluoro488) (ABIN7973149)
抗原
See all BARD1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 709-758
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原理
- Anti-BARD1 Antibody Fluoro488 Conjugated
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交叉反应 （详细）
- No cross-reactivity with other proteins.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human BARD1 recombinant protein (Position: P709-A758).
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亚型
- IgG
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anti-BRCA1 Associated RING Domain 1 (BARD1) (AA 101-200) antibody
BARD1 适用: 人 WB, ELISA, FACS, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-BRCA1 Associated RING Domain 1 (BARD1) (AA 658-757) antibodyBARD1 适用: 人 ELISA, IF 宿主: 小鼠 Monoclonal 2A11 unconjugated
anti-BRCA1 Associated RING Domain 1 (BARD1) antibodyBARD1 适用: 人 WB, FACS 宿主: 小鼠 Monoclonal 25GB8095 unconjugated
anti-BRCA1 Associated RING Domain 1 (BARD1) (AA 101-131), (N-Term) antibodyBARD1 适用: 人 WB 宿主: 兔 Polyclonal RB19063 unconjugated
anti-BRCA1 Associated RING Domain 1 (BARD1) (AA 1-80) antibodyBARD1 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-BRCA1 Associated RING Domain 1 (BARD1) (AA 428-777) antibodyBARD1 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-BRCA1 Associated RING Domain 1 (BARD1) (N-Term) antibodyBARD1 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-BRCA1 Associated RING Domain 1 (BARD1) (N-Term) antibodyBARD1 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-BRCA1 Associated RING Domain 1 (BARD1) (AA 250-300) antibodyBARD1 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-BRCA1 Associated RING Domain 1 (BARD1) antibodyBARD1 适用: 人 WB, IP, DB 宿主: 小鼠 Monoclonal 2059C4a unconjugated
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应用备注
- Flow Cytometry, Optimal dilutions should be determined by end users.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.
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有效期
- 12 months
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- BARD1 (BRCA1 Associated RING Domain 1 (BARD1))
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别名
- BARD1
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背景
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Background: BRCA1-associated RING domain protein 1 is a protein that in humans is encoded by the BARD1 gene. This gene encodes a protein which interacts with the N-terminal region of BRCA1. In addition to its ability to bind BRCA1 in vivo and in vitro, it shares homology with the 2 most conserved regions of BRCA1: the N-terminal RING motif and the C-terminal BRCT domain. The RING motif is a cysteine-rich sequence found in a variety of proteins that regulate cell growth, including the products of tumor suppressor genes and dominant protooncogenes. This protein also contains 3 tandem ankyrin repeats. The BARD1/BRCA1 interaction is disrupted by tumorigenic amino acid substitutions in BRCA1, implying that the formation of a stable complex between these proteins may be an essential aspect of BRCA1 tumor suppression. This protein may be the target of oncogenic mutations in breast or ovarian cancer. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Gene Full Name: BRCA1 associated RING domain 1
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基因ID
- 580
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UniProt
- Q99728
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途径
- DNA Damage Repair
抗原
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