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- 抗原 See all BARD1 抗体
- BARD1 (BRCA1 Associated RING Domain 1 (BARD1))
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This BARD1 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunoprecipitation (IP), Dot Blot (DB)
- 交叉反应
- 人
- 交叉反应 （详细）
- Other species not studied.
- 纯化方法
- Protein G affinity chromatography
- 免疫原
- BARD1 antibody was raised in mouse using recombinant Human Brca1 Associated Ring Domain 1 (Bard1)
- 克隆位点
- 2059C4a
- 亚型
- IgG1
- Top Product
- Discover our top product BARD1 Primary Antibody
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anti-BRCA1 Associated RING Domain 1 (BARD1) (AA 101-200) antibody
BARD1 适用: 人 WB, ELISA, FACS, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-BRCA1 Associated RING Domain 1 (BARD1) (AA 658-757) antibodyBARD1 适用: 人 ELISA, IF 宿主: 小鼠 Monoclonal 2A11 unconjugated
anti-BRCA1 Associated RING Domain 1 (BARD1) (N-Term) antibodyBARD1 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-BRCA1 Associated RING Domain 1 (BARD1) (N-Term) antibodyBARD1 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-BRCA1 Associated RING Domain 1 (BARD1) (AA 428-777) antibodyBARD1 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-BRCA1 Associated RING Domain 1 (BARD1) antibodyBARD1 适用: 小鼠 WB 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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WB: 0.2-2 µg/mL, IP: 100-500 µg/sample
Optimal conditions should be determined by the investigator. - 限制
- 仅限研究用
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- 浓度
- Lot specific
- 缓冲液
- BARD1 antibody in PBS (3.0 mM KCl, 1.5 mM KH2 PO4 , 140 mM NaCl, 8.0 mM Na2 HPO4 (pH 7.4)) containing 1 % bovine serum albumin (BSA) and 0.05 % sodium azide (NaN3 ).
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium Azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- 注意事项
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Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use. - 储存条件
- 4 °C/-20 °C
- 储存方法
- Store at 2-8 °C for up to one year. We recommend long term storage at -20 °C.
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- 抗原
- BARD1 (BRCA1 Associated RING Domain 1 (BARD1))
- 别名
- BARD1 (BARD1 产品)
- 别名
- BARD1 antibody, LOC100147913 antibody, ENSMUSG00000060893 antibody, ENSMUSG00000073653 antibody, BRCA1 associated RING domain 1 antibody, BARD1 antibody, bard1 antibody, Bard1 antibody
- 背景
- BARD1 interacts with the N-terminal region of BRCA1. In addition to its ability to bind BRCA1 in vivo and in vitro, BARD1 shares homology with the 2 most conserved regions of BRCA1: the N-terminal RING motif and the C-terminal BRCT domain. The RING motif is a cysteine-rich sequence found in a variety of proteins that regulate cell growth, including the products of tumor suppressor genes and dominant protooncogenes. The BARD1 protein also contains 3 tandem ankyrin repeats. The BARD1/BRCA1 interaction is disrupted by tumorigenic amino acid substitutions in BRCA1, implying that the formation of a stable complex between these proteins may be an essential aspect of BRCA1 tumor suppression. BARD1 may be the target of oncogenic mutations in breast or ovarian cancer. Synonyms: Monoclonal BARD1 antibody, Anti-BARD1 antibody, BRCA1 associated RING domain gene 1 antibody.
- 途径
- DNA Damage Repair
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