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- 抗原 See all BARD1 抗体
- BARD1 (BRCA1 Associated RING Domain 1 (BARD1))
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抗原表位
- AA 428-777
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This BARD1 antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA
- 交叉反应
- 人
- 纯化方法
- >95%, Protein G purified
- 免疫原
- Recombinant Human BRCA1-associated RING domain protein 1 protein (428-777AA)
- 亚型
- IgG
- Top Product
- Discover our top product BARD1 Primary Antibody
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anti-BRCA1 Associated RING Domain 1 (BARD1) (AA 101-200) antibody
BARD1 适用: 人 WB, ELISA, FACS, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-BRCA1 Associated RING Domain 1 (BARD1) (AA 658-757) antibodyBARD1 适用: 人 ELISA, IF 宿主: 小鼠 Monoclonal 2A11 unconjugated
anti-BRCA1 Associated RING Domain 1 (BARD1) (N-Term) antibodyBARD1 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-BRCA1 Associated RING Domain 1 (BARD1) (N-Term) antibodyBARD1 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-BRCA1 Associated RING Domain 1 (BARD1) antibodyBARD1 适用: 小鼠 WB 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- Recommended dilution: WB:1:500-1:5000,
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4 - 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C,-80 °C
- 储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- 抗原
- BARD1 (BRCA1 Associated RING Domain 1 (BARD1))
- 别名
- BARD1 (BARD1 产品)
- 别名
- BARD1 antibody, LOC100147913 antibody, ENSMUSG00000060893 antibody, ENSMUSG00000073653 antibody, BRCA1 associated RING domain 1 antibody, BARD1 antibody, bard1 antibody, Bard1 antibody
- 背景
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Background: E3 ubiquitin-protein ligase. The BRCA1-BARD1 heterodimer specifically mediates the formation of \'Lys-6\'-linked polyubiquitin chains and coordinates a diverse range of cellular pathways such as DNA damage repair, ubiquitination and transcriptional regulation to maintain genomic stability. Plays a central role in the control of the cell cycle in response to DNA damage. Acts by mediating ubiquitin E3 ligase activity that is required for its tumor suppressor function. Also forms a heterodimer with CSTF1/CSTF-50 to modulate mRNA processing and RNAP II stability by inhibiting pre-mRNA 3\' cleavage.
Aliases: BARD-1 antibody, Bard1 antibody, BARD1_HUMAN antibody, BRCA1 associated RING domain 1 antibody, BRCA1 associated RING domain gene 1 antibody, BRCA1 associated RING domain protein 1 antibody, BRCA1-associated RING domain protein 1 antibody
- UniProt
- Q99728
- 途径
- DNA Damage Repair
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