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Axin 抗体 (AA 1-811) (PE)

This 兔 多克隆 antibody specifically detects Axin in FACS. It exhibits reactivity toward 人.
产品编号 ABIN7971711
发货至: 中国
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Quick Overview for Axin 抗体 (AA 1-811) (PE) (ABIN7971711)

抗原

See all Axin (AXIN1) 抗体
Axin (AXIN1) (Axin 1 (AXIN1))

适用

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宿主

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克隆类型

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多克隆

标记

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This Axin antibody is conjugated to PE

应用范围

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Flow Cytometry (FACS)
  • 抗原表位

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    AA 1-811

    原理

    Anti-AXIN1 Antibody PE Conjugated

    预测反应

    Human AXIN1 shares 86.2%,82.8% amino acid (aa) sequence identity with mouse,rat AXIN1,respectively.

    纯化方法

    Immunogen affinity purified.

    免疫原

    E.coli-derived human AXIN1 recombinant protein (Position: M1-K811). Human AXIN1 shares 86.2% and 82.8% amino acid (aa) sequence identity with mouse and rat AXIN1, respectively.

    亚型

    IgG
  • 应用备注

    Flow Cytometry, Optimal dilutions should be determined by end users.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

    有效期

    12 months
  • 抗原

    Axin (AXIN1) (Axin 1 (AXIN1))

    别名

    AXIN1

    背景

    Background: Axin-1 is a protein that in humans is encoded by the AXIN1 gene. This gene encodes a cytoplasmic protein which contains a regulation of G-protein signaling (RGS) domain and a dishevelled and axin (DIX) domain. The encoded protein interacts with adenomatosis polyposis coli, catenin beta-1, glycogen synthase kinase 3 beta, protein phosphate 2, and itself. This protein functions as a negative regulator of the wingless-type MMTV integration site family, member 1 (WNT) signaling pathway and can induce apoptosis. The crystal structure of a portion of this protein, alone and in a complex with other proteins, has been resolved. Mutations in this gene have been associated with hepatocellular carcinoma, hepatoblastomas, ovarian endometriod adenocarcinomas, and medullablastomas. Alternative splicing results in multiple transcript variants.

    Gene Full Name: axin 1

    基因ID

    8312

    UniProt

    O15169

    途径

    WNT signaling, Sensory Perception of Sound, Regulation of G-Protein Coupled Receptor Protein Signaling
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