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Axin 抗体 (C-Term)

AXIN1 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB31751 unconjugated
产品编号 ABIN655972
发货至: 中国
  • 抗原 See all Axin (AXIN1) 抗体
    Axin (AXIN1) (Axin 1 (AXIN1))
    抗原表位
    • 15
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    • 1
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    AA 710-738, C-Term
    适用
    • 75
    • 53
    • 27
    • 2
    • 1
    宿主
    • 102
    • 6
    • 1
    克隆类型
    • 103
    • 6
    多克隆
    标记
    • 34
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    • 5
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    • 3
    • 1
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    This Axin antibody is un-conjugated
    应用范围
    • 87
    • 48
    • 39
    • 39
    • 26
    • 10
    • 9
    • 8
    • 5
    • 4
    • 2
    • 2
    • 2
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    纯化方法
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    免疫原
    This AXIN1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 710-738 amino acids from the C-terminal region of human AXIN1.
    克隆位点
    RB31751
    亚型
    Ig Fraction
    Top Product
    Discover our top product AXIN1 Primary Antibody
  • 应用备注
    WB: 1:1000. IHC-P: 1:10~50
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
    有效期
    6 months
  • 抗原
    Axin (AXIN1) (Axin 1 (AXIN1))
    别名
    AXIN1 (AXIN1 产品)
    别名
    AXIN1 antibody, axin antibody, fused antibody, xAxin antibody, LOC100226467 antibody, AXIN antibody, PPP1R49 antibody, AI316800 antibody, Axin antibody, Fu antibody, Kb antibody, Ki antibody, kinky antibody, knobbly antibody, AXIN1-RGS antibody, wu:fi22e03 antibody, wu:fj14c08 antibody, wu:fk11b03 antibody, zgc:109872 antibody, axin 1 antibody, axin 1 S homeolog antibody, axin 1 L homeolog antibody, AXIN1 antibody, axin1.S antibody, axin1.L antibody, Axin1 antibody, axin1 antibody
    背景
    This gene encodes a cytoplasmic protein which contains a regulation of G-protein signaling (RGS) domain and a dishevelled and axin (DIX) domain. The encoded protein interacts with adenomatosis polyposis coli, catenin beta-1, glycogen synthase kinase 3 beta, protein phosphate 2, and itself. This protein functions as a negative regulator of the wingless-type MMTV integration site family, member 1 (WNT) signaling pathway and can induce apoptosis. The crystal structure of a portion of this protein, alone and in a complex with other proteins, has been resolved. Mutations in this gene have been associated with hepatocellular carcinoma, hepatoblastomas, ovarian endometriod adenocarcinomas, and medullablastomas. Two transcript variants encoding distinct isoforms have been identified for this gene.
    分子量
    95635
    基因ID
    8312
    NCBI登录号
    NP_003493, NP_851393
    UniProt
    O15169
    途径
    WNT signaling, Sensory Perception of Sound, Regulation of G-Protein Coupled Receptor Protein Signaling
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