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Axin 抗体 (AA 546-752)

AXIN1 适用: 人 WB, ELISA, IHC, ICC, FACS, Neut 宿主: 小鼠 Monoclonal 4F10G1 unconjugated
产品编号 ABIN5611199
发货至: 中国
  • 抗原 See all Axin (AXIN1) 抗体
    Axin (AXIN1) (Axin 1 (AXIN1))
    抗原表位
    • 15
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    AA 546-752
    适用
    • 76
    • 53
    • 27
    • 2
    • 1
    宿主
    • 103
    • 6
    • 1
    小鼠
    克隆类型
    • 104
    • 6
    单克隆
    标记
    • 35
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    • 5
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    • 1
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    This Axin antibody is un-conjugated
    应用范围
    • 88
    • 48
    • 39
    • 39
    • 25
    • 11
    • 9
    • 7
    • 5
    • 5
    • 2
    • 2
    • 1
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    Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunocytochemistry (ICC), Flow Cytometry (FACS), Neutralization (Neut)
    纯化方法
    purified
    免疫原
    Purified recombinant fragment of human 4F10G1 (AA: 546-752) expressed in E. coli.
    克隆位点
    4F10G1
    亚型
    IgG1
    Top Product
    Discover our top product AXIN1 Primary Antibody
  • 应用备注
    ELISA: 1:10000, WB: 1:500 - 1:2000, ICC: N/A, FCM: N/A, IHC: N/A
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Purified antibody in PBS with 0.05 % sodium azide
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C/-20 °C
    储存方法
    4°C, -20°C for long term storage
  • 抗原
    Axin (AXIN1) (Axin 1 (AXIN1))
    别名
    AXIN1 (AXIN1 产品)
    别名
    AXIN1 antibody, axin antibody, fused antibody, xAxin antibody, LOC100226467 antibody, AXIN antibody, PPP1R49 antibody, AI316800 antibody, Axin antibody, Fu antibody, Kb antibody, Ki antibody, kinky antibody, knobbly antibody, AXIN1-RGS antibody, wu:fi22e03 antibody, wu:fj14c08 antibody, wu:fk11b03 antibody, zgc:109872 antibody, axin 1 antibody, axin 1 S homeolog antibody, axin 1 L homeolog antibody, AXIN1 antibody, axin1.S antibody, axin1.L antibody, Axin1 antibody, axin1 antibody
    背景

    Description: This gene encodes a cytoplasmic protein which contains a regulation of G-protein signaling (RGS) domain and a dishevelled and axin (DIX) domain. The encoded protein interacts with adenomatosis polyposis coli, catenin beta-1, glycogen synthase kinase 3 beta, protein phosphate 2, and itself. This protein functions as a negative regulator of the wingless-type MMTV integration site family, member 1 (WNT) signaling pathway and can induce apoptosis. The crystal structure of a portion of this protein, alone and in a complex with other proteins, has been resolved. Mutations in this gene have been associated with hepatocellular carcinoma, hepatoblastomas, ovarian endometriod adenocarcinomas, and medullablastomas. Alternative splicing results in multiple transcript variants.

    Aliases: AXIN, PPP1R49

    分子量
    95.6 kDa
    基因ID
    8312
    HGNC
    8312
    途径
    WNT signaling, Sensory Perception of Sound, Regulation of G-Protein Coupled Receptor Protein Signaling
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