Recombinant JNK 抗体 (pTyr185)
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Quick Overview for Recombinant JNK 抗体 (pTyr185) (ABIN7938300)
抗原
See all JNK (MAPK8) 抗体抗体类型
适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- pTyr185
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原理
- JNK phospho Tyr185 (rAb), 100 μg (Clone 2G8)
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纯化方法
- Protein A Chromatography
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免疫原
- This information is proprietary to Active Motif and/or its suppliers.
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亚型
- IgG
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应用备注
- WB: 1:1000-1:40000 dilution
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限制
- 仅限研究用
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缓冲液
- Purified IgG in PBS, pH 7.3, with 50 % glycerol and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions,Keep all reagents on ice when not in storage
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储存条件
- -20 °C
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储存方法
- Some products may be shipped at room temperature. This will not affect their stability or performance. Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions for storage at -20°C for up to 2 years. Keep all reagents on ice when not in storage.
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有效期
- 24 months
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- JNK (MAPK8) (Mitogen-Activated Protein Kinase 8 (MAPK8))
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别名
- JNK
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背景
- MAPK8 (Mitogen-activated protein kinase 8) is also named JNK1, PRKM8, SAPK1, SAPK1C and belongs to the MAP kinase subfamily. The JNK gene generates 10 forms of JNK through alternative splicing, and the protein encoded by the JNK gene has or does not have a COOH terminal, resulting in 46 kDa and 54 kDa proteins. MAPK8 is activated by dual phosphorylation at a Thr-Pro-Tyr motif during response to UV light. Phosphorylation of these sites in response to UV results in transcriptional activation of c-Jun.
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分子量
- 37-46 kDa
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NCBI登录号
- NM_139049
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途径
- MAPK Pathway, WNT signaling, TLR signaling, Fc-epsilon Receptor Signaling Pathway, Neurotrophin Signaling Pathway, Activation of Innate immune Response, Hepatitis C, Toll-Like Receptors Cascades, Signaling of Hepatocyte Growth Factor Receptor, S100 Proteins
抗原
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