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MAP2K4 抗体 (pSer257)

This anti-MAP2K4 antibody is a 兔 多克隆 antibody detecting MAP2K4 in ELISA, IHC (p), IF (cc), IF (p) 和 IHC (fro). Suitable for 大鼠.
产品编号 ABIN745643
发货至: 中国

Quick Overview for MAP2K4 抗体 (pSer257) (ABIN745643)

抗原

See all MAP2K4 抗体
MAP2K4 (Mitogen-Activated Protein Kinase Kinase 4 (MAP2K4))

适用

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大鼠

宿主

  • 149
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克隆类型

  • 150
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多克隆

标记

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This MAP2K4 antibody is un-conjugated

应用范围

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ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
  • 抗原表位

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    pSer257

    交叉反应

    大鼠

    预测反应

    Human,Mouse,Dog,Cow,Pig,Horse,Chicken,Rabbit

    纯化方法

    Purified by Protein A.

    免疫原

    KLH conjugated synthetic phosphopeptide derived from human SEK1/MKK4 around the phosphorylation site of Ser257

    亚型

    IgG
  • 应用备注

    ELISA 1:500-1000
    IHC-P 1:200-400
    IHC-F 1:100-500
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 μg/μL

    缓冲液

    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

    有效期

    12 months
  • 抗原

    MAP2K4 (Mitogen-Activated Protein Kinase Kinase 4 (MAP2K4))

    别名

    MEK4

    背景

    Synonyms: MEK4 Ser257, MEK4 phospho S257, MEK4 phospho Ser257, p-MEK4 Ser257, c Jun N terminal kinase kinase 1, c-Jun N-terminal kinase kinase 1, c-Jun N-terminal kinase kinase 1, Dual specicity mitogen activated protein kinase kinase 4, Dual specicity mitogen activated protein kinase kinase 4, Dual specicity mitogen-activated protein kinase kinase 4, JNK activated kinase 1, JNK Activated Kinase 1, JNK activating kinase 1, JNK activating kinase 1, JNK-activating kinase 1, JNKK 1, JNKK, JNKK, JNKK-1, JNKK-1, JNKK1, JNKK1, MAP kinase kinase 4, MAP kinase kinase 4, MAP2K4, MAPK / ERK kinase 4, MAPK / ERK kinase 4, MAPK ERK kinase 4, MAPK/ERK kinase 4, MAPKK 4, MAPKK 4, MAPKK-4, MAPKK-4, MAPKK4, MAPKK4, MEK 4, MEK 4, MEK-4, MEK-4, MEK4, Mitogen Activated Protein Kinase Kinase 4, MKK 4, MKK-4, MKK-4, MKK4, MKK4, MP2K4_HUMAN, PRKMK 4, PRKMK 4, PRKMK-4, PRKMK-4, PRKMK4, PRKMK4, SAPK / ERK kinase 1, SAPK / ERK kinase 1, SAPK ERK kinase 1, SAPK/ERK Kinase 1, SEK 1, SEK1, SEK1, SERK 1, SERK-1, SERK-1, SERK1, SERK1.

    Background: This gene encodes a member of the mitogen-activated protein kinase (MAPK) family. Members of this family act as an integration point for multiple biochemical signals and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation, and development. They form a three-tiered signaling module composed of MAPKKKs, MAPKKs, and MAPKs. This protein is phosphorylated at serine and threonine residues by MAPKKKs and subsequently phosphorylates downstream MAPK targets at threonine and tyrosine residues. A similar protein in mouse has been reported to play a role in liver organogenesis. A pseudogene of this gene is located on the long arm of chromosome X. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013]

    基因ID

    6416

    途径

    MAPK Pathway, TLR signaling, Fc-epsilon Receptor Signaling Pathway, Activation of Innate immune Response, Toll-Like Receptors Cascades, BCR Signaling
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