RAF1 抗体 (pSer289)
Quick Overview for RAF1 抗体 (pSer289) (ABIN745343)
抗原
See all RAF1 抗体适用
宿主
克隆类型
标记
应用范围
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    - 
                                            抗原表位
- pSer289
- 
                                            交叉反应
- 小鼠
- 
                                            预测反应
- Human,Rat
- 
                                            纯化方法
- Purified by Protein A.
- 
                                            免疫原
- KLH conjugated synthetic phosphopeptide derived from human c Raf around the phosphorylation site of Ser289
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                                            亚型
- IgG
 
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    - 
                                            应用备注
- 
                        WB 1:300-5000
 ELISA 1:500-1000
 FCM 1:20-100
- 
                                            限制
- 仅限研究用
 
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    - 
                                            状态
- Liquid
- 
                                            浓度
- 1 μg/μL
- 
                                            缓冲液
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
- 
                                            储存液
- ProClin
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                                            注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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                                            储存条件
- 4 °C,-20 °C
- 
                                            储存方法
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
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                                            有效期
- 12 months
 
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    - RAF1 (V-Raf-1 Murine Leukemia Viral Oncogene Homolog 1 (RAF1))
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                                            别名
- c-Raf
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                                            背景
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                        Synonyms: RAF1, murine leukemia viral v-raf-1 oncogene homolog 1 3611-MSV, v-raf-1 murine leukemia viral oncogene homolog 1, cRaf, C-RAF, proto-oncogene c-RAF, 6430402F14Rik, AA990557, BB129353, c-Raf, Craf1, D830050J10Rik, MGC102375, Raf-1, Raf 1, v-Raf, c Raf, Craf 1 transforming gene, Craf1 transforming gene, EC 2.7.11.1, Murine sarcoma 3611 oncogene 1, RAF, Raf proto oncogene serine/threonine protein kinase, vraf1 murine leukemia viral oncogene homolog 1, c-Raf. Background: The Raf family of serine/threonine specific kinases is comprised of three members (aRaf, bRaf, and cRaf) that play a critical role in regulating cell growth and differentiation, and couple growth factor receptor stimulation to nuclear transcription factors via the Ras/mitogen activated protein kinase (MAPK) pathway. cRaf kinase (also known as Raf1) is a small GTPase like kinase of 73 kDa, and is a signal transducer of multiple extracellular stimuli that is regulated by several pathways, and that once activated, phosphorylates MEK which in turn phosphorylates ERK. Raf1 is involved in the transduction of mitogenic signals from the cell membrane to the nucleus. It is part of the Ras dependent signaling pathway from receptors to the nucleus. 
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                                            基因ID
- 5894
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                                            途径
- MAPK Pathway, RTK signaling, Fc-epsilon Receptor Signaling Pathway, Neurotrophin Signaling Pathway, cAMP Metabolic Process, Stem Cell Maintenance, Hepatitis C, Autophagy, Signaling of Hepatocyte Growth Factor Receptor, VEGF Signaling, BCR Signaling
 抗原
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