PIM1 抗体
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北京 101111
Quick Overview for PIM1 抗体 (ABIN7881952)
抗原
See all PIM1 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- PIM1 Antibody
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纯化方法
- Affinity purified
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免疫原
- A synthetic peptide specific to human PIM1 was used as the immunogen for the PIM1 antibody.
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亚型
- IgG
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应用备注
- Optimal dilution of the PIM1 antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Antibody in PBS with 0.02 % sodium azide, 50 % glycerol and 0.4-0.5 mg/mL BSA
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store the PIM1 antibody at -20oC.
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- PIM1 (Pim-1 Oncogene (PIM1))
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别名
- PIM1
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背景
- The protein encoded by the PIM1 gene belongs to the Ser/Thr protein kinase family, and PIM subfamily. This gene is expressed primarily in B-lymphoid and myeloid cell lines, and is overexpressed in hematopoietic malignancies and in prostate cancer. It plays a role in signal transduction in blood cells, contributing to both cell proliferation and survival, and thus provides a selective advantage in tumorigenesis. Both the human and orthologous mouse genes have been reported to encode two isoforms (with preferential cellular localization) resulting from the use of alternative in-frame translation initiation codons, the upstream non-AUG (CUG) and downstream AUG codons. [RefSeq]
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UniProt
- P11309
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途径
- Glycosaminoglycan Metabolic Process
抗原
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