LEF1 抗体
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北京 101111
Quick Overview for LEF1 抗体 (ABIN7881494)
抗原
See all LEF1 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- TCF1 alpha Antibody / T cell specific transcription factor 1 alpha / LEF1
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纯化方法
- Protein A/G affinity
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免疫原
- A recombinant fragment of human LEF1 protein was used as the immunogen for the TCF1 alpha antibody.
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亚型
- IgG1, kappa
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应用备注
- Optimal dilution of the TCF1 alpha antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.2 mg/mL
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缓冲液
- 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Aliquot the TCF1 alpha antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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- LEF1 (Lymphoid Enhancer-Binding Factor 1 (LEF1))
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别名
- TCF1 alpha
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背景
- Lymphoid Enhancing Factor 1 (LEF1), also called TCF1 alpha, is a transcription factor that belongs to the TCF/LEF family. LEF1 participates as a regulator in Wnt signaling pathways. LEF1 is an important factor in lymphopoiesis and is expressed normally in T and pro-B cells but not expressed in mature B cells. Anti-LEF1 may be used as an aid for differentiation of chronic lymphocytic leukemia/small lymphocytic lymphoma from other small B cell lymphomas.
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UniProt
- Q9UJU2
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途径
- WNT signaling, Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Hormone Metabolic Process, Nuclear Hormone Receptor Binding, Chromatin Binding
抗原
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