IRAK1 抗体
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北京 101111
Quick Overview for IRAK1 抗体 (ABIN7881320)
抗原
See all IRAK1 抗体适用
宿主
克隆类型
标记
应用范围
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原理
- IRAK1 Antibody
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序列
- NRNARVADLV HILTHLQLLR ARD
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纯化方法
- Affinity purified
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免疫原
- Amino acids NRNARVADLVHILTHLQLLRARD were used as the immunogen for the IRAK1 antibody.
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亚型
- IgG
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应用备注
- Optimal dilution of the IRAK1 antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Lyophilized
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缓冲液
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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储存条件
- 4 °C,-20 °C
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储存方法
- After reconstitution, the IRAK1 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
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- IRAK1 (Interleukin-1 Receptor-Associated Kinase 1 (IRAK1))
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别名
- IRAK1
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背景
- Interleukin-1 receptor-associated kinase 1, also called IRAK1, is an enzyme that in humans is encoded by the IRAK1 gene. By radiation hybrid analysis, this gene is mapped to chromosome Xq28. Serine/threonine-protein kinase plays a critical role in initiating innate immune response against foreign pathogens. This gene involved in Toll-like receptor (TLR) and IL-1R signaling pathways. This gene encodes the interleukin-1 receptor-associated kinase 1, one of two putative serine/threonine kinases that become associated with the interleukin-1 receptor (IL1R) upon stimulation. This gene is partially responsible for IL1-induced upregulation of the transcription factor NF-kappa B.
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UniProt
- P51617
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途径
- NF-kappaB Signaling, TLR signaling, Neurotrophin Signaling Pathway, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Toll-Like Receptors Cascades
抗原
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