CD51 抗体
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北京 101111
Quick Overview for CD51 抗体 (ABIN7881191)
抗原
See all CD51 (ITGAV) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- ITGAV Antibody / Integrin alpha V / Vitronectin Receptor
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纯化方法
- Affinity purified
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免疫原
- A synthetic peptide specific to human Integrin alpha V / ITGAV was used as the immunogen for the ITGAV antibody.
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亚型
- IgG
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应用备注
- Optimal dilution of the ITGAV antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Antibody in PBS with 0.02 % sodium azide, 50 % glycerol and 0.4-0.5 mg/mL BSA
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store the ITGAV antibody at -20oC.
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- CD51 (ITGAV) (Integrin alpha V (ITGAV))
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别名
- ITGAV
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背景
- The product of this gene belongs to the integrin alpha chain family. Integrins are heterodimeric integral membrane proteins composed of an alpha subunit and a beta subunit that function in cell surface adhesion and signaling. The encoded preproprotein is proteolytically processed to generate light and heavy chains that comprise the alpha V subunit. This subunit associates with beta 1, beta 3, beta 5, beta 6 and beta 8 subunits. The heterodimer consisting of alpha V and beta 3 subunits is also known as the vitronectin receptor. This integrin may regulate angiogenesis and cancer progression. Alternative splicing results in multiple transcript variants. Note that the integrin alpha 5 and integrin alpha V subunits are encoded by distinct genes. [RefSeq]
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UniProt
- P06756
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途径
- Cell-Cell Junction Organization, Signaling Events mediated by VEGFR1 and VEGFR2, Growth Factor Binding, Integrin Complex
抗原
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