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HLA-ABC 抗体

The 小鼠 单克隆 anti-HLA-ABC antibody (Clone Bra-23-9) (ABIN7881088) specifically detects HLA-ABC in FACS 和 IF. The antibody is reactive with 人 samples.
产品编号 ABIN7881088
发货至: 中国
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Quick Overview for HLA-ABC 抗体 (ABIN7881088)

抗原

See all HLA-ABC 抗体
HLA-ABC

适用

  • 90
  • 28
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  • 7
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宿主

  • 67
  • 18
  • 4
  • 1
小鼠

克隆类型

  • 80
  • 9
单克隆

标记

  • 44
  • 7
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  • 7
  • 5
  • 2
  • 2
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  • 1
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This HLA-ABC antibody is un-conjugated

应用范围

  • 64
  • 18
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  • 10
  • 6
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  • 1
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Flow Cytometry (FACS), Immunofluorescence (IF)

克隆位点

Bra-23-9
  • 原理

    HLA-ABC Antibody

    纯化方法

    Protein A/G affinity

    免疫原

    Human REH cells (a pre-B leukaemia cell line) was used as the immunogen for the HLA-ABC antibody.

    亚型

    IgG2a, kappa
  • 应用备注

    Optimal dilution of the HLA-ABC antibody should be determined by the researcher.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.2 mg/mL

    缓冲液

    0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05 % sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Aliquot the HLA-ABC antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
  • 抗原

    HLA-ABC

    别名

    HLA-ABC

    背景

    Reacts with a monomorphic determinant of human major histocompatibility (MHC) class I antigens (HLA-A, B and C). Immunoprecipitation of lactoperoxidase radioiodinated cell surface proteins and surface sialoglycoproteins radiolabeled by sodium metaperiodate/tritiated sodium borohydride technique confirmed the structure gp44,p12 (consisting of a 44 kDa glycopeptide linked with a non-glycosylated 12 kDa peptide) typical for MHC class I antigen(s) as a structure recognized by Bra23/9. Human MHC class I antigens are expressed constitutively on all nucleated cells lymphocytes such as lymphocytes, thymocytes, granulocytes, and bone marrow cells and are absent on erythrocytes. MHC class I antigens play a role in class I MHC-associated antigen presentation, inhibition of NK cell cytotoxicity, tumor surveillance, and tissue allotransplantation.

    UniProt

    P01889

    途径

    TCR Signaling, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Cancer Immune Checkpoints
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