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GTPase NRas 抗体

The 兔 单克隆 anti-GTPase NRas antibody is suitable to detect GTPase NRas in samples from 人 和 大鼠. It has been validated for WB.
产品编号 ABIN7880943
发货至: 中国
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中国
北京 101111
No. 88 KeChuang 6th Street
Beijing Economic Technological Development Area
Room 801-803
4A Biotech Co.,Ltd.
Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for GTPase NRas 抗体 (ABIN7880943)

抗原

See all GTPase NRas (NRAS) 抗体
GTPase NRas (NRAS)

适用

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人, 大鼠

宿主

  • 43
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克隆类型

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单克隆

标记

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This GTPase NRas antibody is un-conjugated

应用范围

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Western Blotting (WB)

克隆位点

DBC-14
  • 原理

    NRAS Antibody

    纯化方法

    Affinity purified

    免疫原

    A synthetic peptide specific to human NRAS was used as the immunogen for the NRAS antibody.

    亚型

    IgG
  • 应用备注

    Optimal dilution of the NRAS antibody should be determined by the researcher.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Antibody in PBS with 0.02 % sodium azide, 50 % glycerol and 0.4-0.5 mg/mL BSA

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store the NRAS antibody at -20oC.
  • 抗原

    GTPase NRas (NRAS)

    别名

    NRAS

    背景

    NRAS is a membrane protein that shuttles between the Golgi apparatus and the plasma membrane. This shuttling is regulated through palmitoylation and depalmitoylation by the ZDHHC9-GOLGA7 complex. It has intrinsic GTPase activity, is activated by a guanine nucleotide-exchange factor and inactivated by a GTPase activating protein. Mutations in the gene have been associated with somatic rectal cancer, follicular thyroid cancer, autoimmune lymphoproliferative syndrome, Noonan syndrome, and juvenile myelomonocytic leukemia. [RefSeq]

    UniProt

    P01111

    途径

    p53 Pathway, MAPK Pathway, RTK signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Hepatitis C, Regulation of long-term Neuronal Synaptic Plasticity, VEGF Signaling
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