Recombinant C1QA 抗体
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北京 101111
Quick Overview for Recombinant C1QA 抗体 (ABIN7880493)
抗原
See all C1QA 抗体抗体类型
适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- C1QA Antibody / Complement component 1 subcomponent subunit A
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纯化方法
- Affinity-chromatography
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免疫原
- A synthesized peptide derived from human C1QA was used as the immunogen for the C1QA antibody.
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亚型
- IgG
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anti-Complement Component 1, Q Subcomponent, A Chain (C1QA) (AA 23-245) antibody
C1QA 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Complement Component 1, Q Subcomponent, A Chain (C1QA) (AA 23-167) antibodyC1QA 适用: 人 IHC, ELISA, FACS 宿主: 小鼠 Monoclonal 8B5B1 unconjugated
anti-Complement Component 1, Q Subcomponent, A Chain (C1QA) (AA 28-245) antibodyC1QA 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Complement Component 1, Q Subcomponent, A Chain (C1QA) (AA 23-167) antibodyC1QA 适用: 人 IHC, ELISA, FACS 宿主: 小鼠 Monoclonal 1C7G3 unconjugated
anti-Complement Component 1, Q Subcomponent, A Chain (C1QA) (AA 104-237) antibodyC1QA 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal C1QA-2783 unconjugated
anti-Complement Component 1, Q Subcomponent, A Chain (C1QA) (AA 104-237) antibodyC1QA 适用: 人 IHC 宿主: 小鼠 Monoclonal C1QA-2952 unconjugated
anti-Complement Component 1, Q Subcomponent, A Chain (C1QA) (AA 96-245) antibodyC1QA 适用: 人 ELISA, FACS 宿主: 小鼠 Monoclonal 1C9G9 unconjugated
anti-Complement Component 1, Q Subcomponent, A Chain (C1QA) (AA 1-245) antibodyC1QA 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-Complement Component 1, Q Subcomponent, A Chain (C1QA) (AA 23-245) antibodyC1QA 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Complement Component 1, Q Subcomponent, A Chain (C1QA) (AA 26-125) antibodyC1QA 适用: 人 IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal dilution of the C1QA antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Rabbit IgG in phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol, 0.4-0.5 mg/mL BSA
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store the C1QA antibody at -20oC.
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- C1QA (Complement Component 1, Q Subcomponent, A Chain (C1QA))
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别名
- C1QA
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背景
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C1QA antibody detects complement component 1 subcomponent subunit A, encoded by the C1QA gene. C1QA is one of three chains (A, B, and C) that assemble to form the C1q protein complex, a recognition unit of the classical complement pathway. C1q binds to antibodies or immune complexes, initiating complement activation and promoting clearance of pathogens and apoptotic cells. Through these roles, C1QA is central to innate immunity and host defense.
C1QA antibody is commonly used in immunology, inflammation, and autoimmune disease research. C1QA expression is highest in monocytes, macrophages, and dendritic cells. It functions as a pattern recognition receptor that bridges innate and adaptive immunity. By detecting C1QA, researchers can study activation of complement pathways and regulation of immune responses.
In western blot assays, C1QA antibody detects protein bands of expected size in immune cell extracts. Immunohistochemistry highlights strong expression in macrophages and tissue resident immune cells. Immunofluorescence enables visualization of C1QA in immune synapses and complement activation sites. ELISA supports quantification of circulating C1QA in biological samples.
Deficiency of C1QA is associated with autoimmune disorders such as systemic lupus erythematosus, underscoring its importance in self tolerance and immune clearance. Elevated expression of C1QA has been linked to chronic inflammation and neurodegenerative diseases, including Alzheimer disease, where complement activation contributes to pathology. By applying C1QA antibody, scientists can investigate how alterations in complement regulation affect health and disease.
C1QA antibody from NSJ Bioreagents offers reliable specificity for complement research. Its performance across methods ensures accurate detection of this key immune recognition protein. -
UniProt
- P02745
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途径
- Complement System
抗原
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