C1QA 抗体 (AA 104-237)
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- 抗原 See all C1QA 抗体
- C1QA (Complement Component 1, Q Subcomponent, A Chain (C1QA))
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抗原表位
- AA 104-237
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This C1QA antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA, Coating (Coat)
- 纯化方法
- Purified by Protein A/G
- 免疫原
- Recombinant fragment (around aa 104-237) of human C1QA protein (exact sequence is proprietary)
- 克隆位点
- C1QA-2783
- 亚型
- IgG2b kappa
- Top Product
- Discover our top product C1QA Primary Antibody
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- 应用备注
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Positive Control: HepG2 or PC3 cell lysate. Human spleen or liver tissue lysates (WB).
Known Application: ELISA (For coating, order Ab without BSA), Western Blot (1-2 μg/mL)Optimal dilution for a specific application should be determined.
- 限制
- 仅限研究用
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- 浓度
- 200 μg/mL
- 缓冲液
- 10 mM PBS with 0.05 % BSA & 0.05 % azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-80 °C
- 储存方法
- Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
- 有效期
- 24 months
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- 抗原
- C1QA (Complement Component 1, Q Subcomponent, A Chain (C1QA))
- 别名
- C1QA (C1QA 产品)
- 别名
- zgc:109903 antibody, C1QA antibody, AI255395 antibody, C1q antibody, complement C1q A chain antibody, complement component 1, q subcomponent, A chain antibody, complement component 1, q subcomponent, alpha polypeptide antibody, C1QA antibody, c1qa antibody, C1qa antibody
- 背景
- C1q, a subcomponent of the classical complement pathway, is composed of nine subunits that mediate classical complement activation and thereby play an important role in the immune response. Six of these subunits are disulfide-linked dimers of chains A and B, while three of these subunits, designated C1q-A through C1q-C, are disulfide-linked dimers of chain C. Each chain contains an N-terminal collagen-like region and a C-terminal C1q globular domain. The presence of receptors for C1q on effector cells modulates its activity, which may be antibody-dependent or independent. Macrophages are the primary source of C1q, while anti-inflammatory drugs as well as cytokines differentially regulate expression of the mRNA as well as the protein. C1q deficiency is associated with lupus erythematosus and glomerulonephritis.
- 分子量
- 29kDa
- 基因ID
- 712
- UniProt
- P02745
- 途径
- Complement System
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