Ephrin A1 抗体 (AA 83-115)
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北京 101111
Quick Overview for Ephrin A1 抗体 (AA 83-115) (ABIN7876931)
抗原
See all Ephrin A1 (EFNA1) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 83-115
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原理
- EFNA1 Antibody / Ephrin A1
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免疫原
- A portion of amino acids 83-115 from the human protein was used as the immunogen for the EFNA1 antibody.
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亚型
- Ig Fraction
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anti-Ephrin A1 (EFNA1) (Internal Region) antibody
EFNA1 适用: 人, 大鼠, 小鼠 ELISA, WB, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Ephrin A1 (EFNA1) (AA 19-182) antibodyEFNA1 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Ephrin A1 (EFNA1) antibodyEFNA1 适用: 人 WB, IHC, IF 宿主: 兔 Monoclonal unconjugated
anti-Ephrin A1 (EFNA1) (AA 150-164), (Extracellular) antibodyEFNA1 适用: 人 WB, IF, FACS, IC, LCI 宿主: 兔 Polyclonal unconjugated
anti-Ephrin A1 (EFNA1) (AA 19-182) antibodyEFNA1 适用: 人 ELISA, WB, IHC (p), IHC (fro), ICC 宿主: 兔 Polyclonal unconjugated
anti-Ephrin A1 (EFNA1) (AA 19-182) antibodyEFNA1 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Ephrin A1 (EFNA1) antibodyKD Validated EFNA1 适用: 人 WB 宿主: 兔 Monoclonal 23GB5265 unconjugated Recombinant Antibody
anti-Ephrin A1 (EFNA1) (Internal Region) antibodyEFNA1 适用: 人, 大鼠, 小鼠 ELISA, WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Ephrin A1 (EFNA1) antibodyEFNA1 适用: 人, 大鼠, 小鼠 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Ephrin A1 (EFNA1) (AA 101-205) antibodyEFNA1 适用: 人 ELISA, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
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应用备注
- The stated application concentrations are suggested starting points. Titration of the EFNA1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- In 1X PBS, pH 7.4, with 0.09 % sodium azide and 50 % glycerol
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store the EFNA1 antibody at -20oC.
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- Ephrin A1 (EFNA1)
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别名
- EFNA1
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背景
- Ephrin A1 is a membrane-bound protein that interacts with Eph receptors on neighboring cells, initiating a cascade of signals that regulate cell behavior and movement. This interaction is essential for processes such as cell migration, tissue organization, and synaptic connectivity in the nervous system. Studies have shown that dysregulation of Ephrin A1 signaling can lead to aberrant cell growth, invasion, and metastasis in cancer cells, highlighting its importance in disease progression. One of the key features of Ephrin A1 is its ability to both attract and repel cells, depending on the context and concentration of the molecule. This dual role allows Ephrin A1 to fine-tune cell-cell interactions and ensure proper tissue patterning during development. In the brain, for example, Ephrin A1 guides axonal growth and synapse formation, shaping the intricate neural circuits that underlie cognitive functions. In addition to its role in development, Ephrin A1 has also been implicated in several disease processes. Aberrant expression of EFNA1 has been observed in various types of cancer, including breast, lung, and colon cancer, where it promotes tumor growth and invasion. In neurodegenerative disorders such as Alzheimer's disease, dysregulation of Ephrin A1 signaling disrupts synaptic connectivity and contributes to cognitive decline.
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UniProt
- P20827
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途径
- RTK signaling
抗原
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