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KAP1 抗体 (AA 699-835)

The 小鼠 单克隆 anti-KAP1 antibody (Clone 3H2) (ABIN7876462) specifically detects KAP1 in WB, IF, FACS, IHC (p) 和 IHC (fro). The antibody is reactive with 人, 小鼠 和 大鼠 samples.
产品编号 ABIN7876462
发货至: 中国
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Quick Overview for KAP1 抗体 (AA 699-835) (ABIN7876462)

抗原

See all KAP1 (TRIM28) 抗体
KAP1 (TRIM28) (Tripartite Motif Containing 28 (TRIM28))

适用

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人, 小鼠, 大鼠

宿主

  • 137
  • 19
  • 4
  • 1
小鼠

克隆类型

  • 110
  • 51
单克隆

标记

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  • 5
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This KAP1 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunofluorescence (IF), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

克隆位点

3H2
  • 抗原表位

    • 30
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    • 6
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    • 2
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    • 1
    • 1
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    • 1
    • 1
    • 1
    • 1
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    AA 699-835

    原理

    TRIM28 Antibody / KAP1

    纯化方法

    Affinity purified

    免疫原

    Recombinant human protein (amino acids A699-P835) was used as the immunogen for the TRIM28 antibody.

    亚型

    IgG2b
  • 应用备注

    Optimal dilution of the TRIM28 antibody should be determined by the researcher.

    限制

    仅限研究用
  • 状态

    Lyophilized

    缓冲液

    0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

    储存条件

    4 °C,-20 °C

    储存方法

    After reconstitution, the TRIM28 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
  • 抗原

    KAP1 (TRIM28) (Tripartite Motif Containing 28 (TRIM28))

    别名

    TRIM28

    背景

    Tripartite motif-containing 28 (TRIM28), also known as transcriptional intermediary factor 1 beta (TIF1b) and KAP1 (KRAB-associated protein-1), is a protein that in humans is encoded by the TRIM28 gene. The protein encoded by this gene mediates transcriptional control by interaction with the Kruppel-associated box repression domain found in many transcription factors. The protein localizes to the nucleus and is thought to associate with specific chromatin regions. KAP1 is a ubiquitously expressed protein involved in many critical functions including: transcriptional regulation, cellular differentiation and proliferation, DNA damage repair, viral suppression, and apoptosis. Its functionality is dependent upon post-translational modifications. Phosphorylation of KAP1 acts as a deactivator of the protein in many of its mechanisms while sumoylation acts as an activator.

    UniProt

    Q13263

    途径

    Hedgehog Signaling, Positive Regulation of Response to DNA Damage Stimulus
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