KAP1 抗体 (AA 699-835)
Our Local Distributor
北京 101111
Quick Overview for KAP1 抗体 (AA 699-835) (ABIN7876461)
抗原
See all KAP1 (TRIM28) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
-
-
抗原表位
- AA 699-835
-
原理
- TRIM28 Antibody / KAP1
-
纯化方法
- Affinity purified
-
免疫原
- Recombinant human protein (amino acids A699-P835) was used as the immunogen for the TRIM28 antibody.
-
亚型
- IgG2a
-
-
-
-
应用备注
- Optimal dilution of the TRIM28 antibody should be determined by the researcher.
-
限制
- 仅限研究用
-
-
-
状态
- Lyophilized
-
缓冲液
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
-
储存条件
- 4 °C,-20 °C
-
储存方法
- After reconstitution, the TRIM28 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
-
-
- KAP1 (TRIM28) (Tripartite Motif Containing 28 (TRIM28))
-
别名
- TRIM28
-
背景
- Tripartite motif-containing 28 (TRIM28), also known as transcriptional intermediary factor 1 beta (TIF1b) and KAP1 (KRAB-associated protein-1), is a protein that in humans is encoded by the TRIM28 gene. The protein encoded by this gene mediates transcriptional control by interaction with the Kruppel-associated box repression domain found in many transcription factors. The protein localizes to the nucleus and is thought to associate with specific chromatin regions. KAP1 is a ubiquitously expressed protein involved in many critical functions including: transcriptional regulation, cellular differentiation and proliferation, DNA damage repair, viral suppression, and apoptosis. Its functionality is dependent upon post-translational modifications. Phosphorylation of KAP1 acts as a deactivator of the protein in many of its mechanisms while sumoylation acts as an activator.
-
UniProt
- Q13263
-
途径
- Hedgehog Signaling, Positive Regulation of Response to DNA Damage Stimulus
抗原
-