ITK 抗体 (AA 49-465)
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Quick Overview for ITK 抗体 (AA 49-465) (ABIN7875257)
抗原
See all ITK 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 49-465
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原理
- IL2-inducible T-cell kinase Antibody / ITK
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纯化方法
- Antigen affinity purified
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免疫原
- E. coli-derived recombinant human protein (amino acids R49-F465) was used as the immunogen for the IL2-inducible T-cell kinase antibody.
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亚型
- IgG
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应用备注
- Optimal dilution of the IL2-inducible T-cell kinase antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Lyophilized
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缓冲液
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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储存条件
- 4 °C,-20 °C
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储存方法
- After reconstitution, the IL2-inducible T-cell kinase antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
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- ITK (IL2-Inducible T-Cell Kinase (ITK))
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别名
- IL2-inducible T-cell kinase
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背景
- Tyrosine-protein kinase ITK/TSK, also known as interleukin-2-inducible T-cell kinase or simply ITK, is a protein that in humans is encoded by the ITK gene. It is a member of the TEC family of kinases. This gene is mapped to 5q33.3. This gene encodes an intracellular tyrosine kinase expressed in T-cells. The protein is thought to play a role in T-cell proliferation and differentiation. Furthermore, ITK is functionally important for the development and effector function of Th2 and Th17 cells.
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UniProt
- Q08881
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途径
- TCR Signaling, Fc-epsilon Receptor Signaling Pathway
抗原
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