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IGF1 抗体 (AA 45-161)

Name: IGF1 抗体 (AA 45-161)
SKU: ABIN7875056
Availability: OutOfStock

This 兔多克隆 antibody specifically detects IGF1 in IHC (p). It exhibits reactivity toward 斑马鱼.

产品编号 ABIN7875056

发货至: 中国

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Quick Overview for IGF1 抗体 (AA 45-161) (ABIN7875056)

抗原

See all IGF1 抗体

IGF1 (Insulin-Like Growth Factor 1 (IGF1))

适用

斑马鱼

宿主

兔

克隆类型

多克隆

标记

This IGF1 antibody is un-conjugated

应用范围

Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Discover our top product IGF1 Primary Antibody

抗原表位
24

15

15

9

4

4

3

3

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
AA 45-161

原理

Zebrafish Insulin like growth factor 1 Antibody / Igf1

纯化方法

Antigen affinity chromatography

免疫原

E. coli-derived zebrafish Insulin like growth factor 1 recombinant protein (amino acids G45-M161) was used as the immunogen for the Zebrafish Insulin like growth factor 1 antibody.

亚型

Ig Fraction
anti-Insulin-Like Growth Factor 1 (IGF1) (AA 49-118) antibody
IGF1 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

anti-Insulin-Like Growth Factor 1 (IGF1) (AA 49-118) antibody
IGF1 适用: 人 WB, IHC, IP, ICC 宿主: 小鼠 Monoclonal C10 unconjugated

anti-Insulin-Like Growth Factor 1 (IGF1) (AA 49-118) antibody
IGF1 适用: 人 WB, ICC, IF 宿主: 小鼠 Monoclonal C1 unconjugated

anti-Insulin-Like Growth Factor 1 (IGF1) (AA 49-153) antibody
IGF1 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

anti-Insulin-Like Growth Factor 1 (IGF1) (Internal Region) antibody
Verified IGF1 适用: 人 WB, IHC, ELISA, IF, FACS 宿主: 山羊 Polyclonal unconjugated

anti-Insulin-Like Growth Factor 1 (IGF1) (AA 115-144), (C-Term) antibody
IGF1 适用: 人 WB, IF, FACS, IHC (p) 宿主: 兔 Polyclonal RB33711 unconjugated

anti-Insulin-Like Growth Factor 1 (IGF1) (AA 115-144) antibody
IGF1 适用: 人 WB, IHC, ELISA, IF, FACS 宿主: 兔 Polyclonal unconjugated

anti-Insulin-Like Growth Factor 1 (IGF1) (AA 49-100) antibody
IGF1 适用: 人, 小鼠, 大鼠, 犬 WB, IP, ELISA, IHC (p), IF (p), IF (cc), IHC (fro) 宿主: 兔 Polyclonal unconjugated

anti-Insulin-Like Growth Factor 1 (IGF1) (AA 33-102) antibody
IGF1 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

anti-Insulin-Like Growth Factor 1 (IGF1) (AA 50-150) antibody
IGF1 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated

应用备注

Optimal dilution of the Zebrafish Insulin like growth factor 1 antibody should be determined by the researcher.

限制

仅限研究用
状态

Lyophilized

缓冲液

0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

储存条件

4 °C,-20 °C

储存方法

After reconstitution, the Zebrafish Insulin like growth factor 1 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
抗原

IGF1 (Insulin-Like Growth Factor 1 (IGF1))

别名

Insulin like growth factor 1

背景

Insulin like growth factor 1, also known as IGF1, is a peptide growth factor that plays a key role in regulating cell growth, differentiation, and survival. In zebrafish, insulin like growth factor 1 is essential for normal embryonic development, tissue regeneration, and metabolic regulation.
IGF1 is produced mainly in the liver and acts both locally and systemically through endocrine and paracrine signaling. It mediates many of the growth promoting effects of growth hormone and functions by binding to its specific receptor on the cell surface, triggering downstream signaling pathways that influence cell cycle progression, protein synthesis, and apoptosis inhibition.
In zebrafish, insulin like growth factor 1 is involved in the development of multiple organs including the brain, heart, and skeletal muscle. It also supports fin regeneration and contributes to recovery from injury by promoting cell proliferation and tissue remodeling. IGF1 expression is sensitive to nutritional status and environmental factors, making it a key biomarker for growth and metabolic studies.
Due to its strong conservation across vertebrates and its broad physiological importance, zebrafish insulin like growth factor 1 is widely used in research related to developmental biology, growth regulation, endocrine function, metabolic disease, and regenerative medicine.

UniProt

Q90VV9

途径

RTK signaling, Intracellular Steroid Hormone Receptor Signaling Pathway, Peptide Hormone Metabolism, Hormone Activity, Regulation of Intracellular Steroid Hormone Receptor Signaling, Regulation of Hormone Metabolic Process, Regulation of Hormone Biosynthetic Process, Stem Cell Maintenance, Glycosaminoglycan Metabolic Process, Regulation of Carbohydrate Metabolic Process, Autophagy, Smooth Muscle Cell Migration, Activated T Cell Proliferation, Positive Regulation of fat Cell Differentiation