MCM2 抗体 (AA 381-835)
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Quick Overview for MCM2 抗体 (AA 381-835) (ABIN7874525)
抗原
See all MCM2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 381-835
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原理
- Zebrafish Mcm2 Antibody
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纯化方法
- Antigen affinity chromatography
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免疫原
- An E.coli-derived zebrafish Mcm2 recombinant protein (amino acids A381-R835) was used as the immunogen for the Zebrafish Mcm2 antibody.
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亚型
- Ig Fraction
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应用备注
- Optimal dilution of the Zebrafish Mcm2 antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Lyophilized
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缓冲液
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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储存条件
- 4 °C,-20 °C
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储存方法
- After reconstitution, the Zebrafish Mcm2 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
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- MCM2 (Minichromosome Maintenance Complex Component 2 (MCM2))
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别名
- Mcm2
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背景
- MCM2 (MINICHROMOSOME MAINTENANCE, S. CEREVISIAE, HOMOLOG OF, 2), also known as MITOTIN, CDCL1 or BM28, is a human nuclear protein that plays an important role in 2 crucial steps of the cell cycle, namely, onset of DNA replication and cell division. And it is similar to members of the family of early S-phase proteins. The MCM2 gene is mapped to 3q21.3. The hexameric protein complex formed by MCM proteins is a key component of the pre-replication complex (pre-RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. In the G0 stage, the MCM2 and MCM5 proteins were much less abundant than the MCM7 and MCM3 proteins, which suggests that the MCM proteins are not present in stoichiometric amounts and that only a proportion of these molecules actively participate in cell cycle regulation as part of MCM complexes.
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途径
- DNA Damage Repair, Mitotic G1-G1/S Phases, DNA Replication, Chromatin Binding, Synthesis of DNA
抗原
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