SPTA1 抗体 (AA 356-475)
Our Local Distributor
北京 101111
Quick Overview for SPTA1 抗体 (AA 356-475) (ABIN7874270)
抗原
See all SPTA1 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
-
-
抗原表位
- AA 356-475
-
原理
- SPTA1 Antibody / Spectrin alpha 1
-
纯化方法
- Protein G affinity chromatography
-
免疫原
- A portion of amino acids 356-475 from the human protein was used as the immunogen for the SPTA1 antibody.
-
亚型
- IgG2b, kappa
-
-
-
-
应用备注
- Optimal dilution of the SPTA1 antibody should be determined by the researcher.
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- 0.2 mg/mL
-
缓冲液
- 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05 % sodium azide
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- 4 °C,-20 °C
-
储存方法
- Store the SPTA1 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
-
-
- SPTA1 (Spectrin alpha 1, Erythrocytic (SPTA1))
-
别名
- SPTA1
-
背景
- Spectrin is an actin crosslinking and molecular scaffold protein that links the plasma membrane to the actin cytoskeleton, and functions in the determination of cell shape, arrangement of transmembrane proteins, and organization of organelles. Spectrins function as membrane organizers and stabilizers, composed of non-homologous and chains, which aggregate side-to-side in an anti-parallel fashion to form dimers, tetramers and higher polymers. Spectrin Ia and spectrin Ib are present in erythrocytes, whereas spectrin IIa (also designated fodrin alpha) and spectrin IIb (also designated fodrin beta) are present in other somatic cells. The spectrin tetramers in erythrocytes act as barriers to lateral diffusion, but spectrin dimers seem to lack this function.
-
UniProt
- P02549
-
途径
- Regulation of Actin Filament Polymerization
抗原
-