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SPTA1 抗体 (AA 356-475)

The 小鼠 单克隆 anti-SPTA1 antibody is suitable to detect SPTA1 in samples from 人. It has been validated for WB, ELISA 和 IHC (p).
产品编号 ABIN7874268
发货至: 中国
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Quick Overview for SPTA1 抗体 (AA 356-475) (ABIN7874268)

抗原

See all SPTA1 抗体
SPTA1 (Spectrin alpha 1, Erythrocytic (SPTA1))

适用

  • 86
  • 22
  • 14
  • 1
  • 1
  • 1
  • 1

宿主

  • 47
  • 40
小鼠

克隆类型

  • 73
  • 14
单克隆

标记

  • 30
  • 7
  • 4
  • 4
  • 4
  • 4
  • 4
  • 4
  • 4
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 2
  • 2
This SPTA1 antibody is un-conjugated

应用范围

  • 65
  • 60
  • 36
  • 14
  • 12
  • 11
  • 11
  • 3
  • 3
  • 2
  • 2
  • 2
Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

克隆位点

SPTA1-1832
  • 抗原表位

    • 47
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 356-475

    原理

    Spectrin alpha 1 Antibody / SPTA1

    纯化方法

    Protein G affinity chromatography

    免疫原

    A portion of amino acids 356-475 from the human protein was used as the immunogen for the Spectrin alpha 1 antibody.

    亚型

    IgG2b, kappa
  • 应用备注

    Optimal dilution of the Spectrin alpha 1 antibody should be determined by the researcher.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.2 mg/mL

    缓冲液

    0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05 % sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store the Spectrin alpha 1 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
  • 抗原

    SPTA1 (Spectrin alpha 1, Erythrocytic (SPTA1))

    别名

    Spectrin alpha 1

    背景

    Spectrin is an actin crosslinking and molecular scaffold protein that links the plasma membrane to the actin cytoskeleton, and functions in the determination of cell shape, arrangement of transmembrane proteins, and organization of organelles. Spectrins function as membrane organizers and stabilizers, composed of non-homologous and chains, which aggregate side-to-side in an anti-parallel fashion to form dimers, tetramers and higher polymers. Spectrin Ia and spectrin Ib are present in erythrocytes, whereas spectrin IIa (also designated fodrin alpha) and spectrin IIb (also designated fodrin beta) are present in other somatic cells. The spectrin tetramers in erythrocytes act as barriers to lateral diffusion, but spectrin dimers seem to lack this function.

    UniProt

    P02549

    途径

    Regulation of Actin Filament Polymerization
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