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SPTA1 抗体 (AA 356-475)

This 小鼠 单克隆 antibody specifically detects SPTA1 in WB, ELISA 和 IHC (p). It exhibits reactivity toward 人.
产品编号 ABIN7874267
发货至: 中国
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Quick Overview for SPTA1 抗体 (AA 356-475) (ABIN7874267)

抗原

See all SPTA1 抗体
SPTA1 (Spectrin alpha 1, Erythrocytic (SPTA1))

适用

  • 86
  • 22
  • 14
  • 1
  • 1
  • 1
  • 1

宿主

  • 47
  • 40
小鼠

克隆类型

  • 73
  • 14
单克隆

标记

  • 30
  • 7
  • 4
  • 4
  • 4
  • 4
  • 4
  • 4
  • 4
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 2
  • 2
This SPTA1 antibody is un-conjugated

应用范围

  • 65
  • 60
  • 36
  • 14
  • 12
  • 11
  • 11
  • 3
  • 3
  • 2
  • 2
  • 2
Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

质量等级

Carrier-free

克隆位点

SPTA1-1832
  • 抗原表位

    • 47
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 356-475

    原理

    Spectrin alpha 1 Antibody / SPTA1 (azide and preservative free)

    纯化方法

    Protein G affinity chromatography

    免疫原

    A portion of amino acids 356-475 from the human protein was used as the immunogen for the Spectrin alpha 1 antibody.

    亚型

    IgG2b, kappa
  • 应用备注

    Optimal dilution of the Spectrin alpha 1 antibody should be determined by the researcher.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    1 mg/mL in 1X PBS, BSA free, sodium azide free

    储存液

    Azide free

    储存条件

    4 °C,-20 °C

    储存方法

    Store the Spectrin alpha 1 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
  • 抗原

    SPTA1 (Spectrin alpha 1, Erythrocytic (SPTA1))

    别名

    Spectrin alpha 1

    背景

    Spectrin is an actin crosslinking and molecular scaffold protein that links the plasma membrane to the actin cytoskeleton, and functions in the determination of cell shape, arrangement of transmembrane proteins, and organization of organelles. Spectrins function as membrane organizers and stabilizers, composed of non-homologous and chains, which aggregate side-to-side in an anti-parallel fashion to form dimers, tetramers and higher polymers. Spectrin Ia and spectrin Ib are present in erythrocytes, whereas spectrin IIa (also designated fodrin alpha) and spectrin IIb (also designated fodrin beta) are present in other somatic cells. The spectrin tetramers in erythrocytes act as barriers to lateral diffusion, but spectrin dimers seem to lack this function.

    UniProt

    P02549

    途径

    Regulation of Actin Filament Polymerization
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