DDR1 抗体 (AA 341-909)
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Quick Overview for DDR1 抗体 (AA 341-909) (ABIN7874100)
抗原
See all DDR1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 341-909
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原理
- DDR1 Antibody
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纯化方法
- Affinity purified
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免疫原
- A human recombinant protein (amino acids R341-A909) was used as the immunogen for the DDR1 antibody.
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亚型
- IgG
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anti-Discoidin Domain Receptor tyrosine Kinase 1 (DDR1) (AA 299-330) antibody
DDR1 适用: 人 WB, IHC (p), FACS, IF 宿主: 兔 Polyclonal RB14442 unconjugated
anti-Discoidin Domain Receptor tyrosine Kinase 1 (DDR1) (AA 17-47), (N-Term) antibodyDDR1 适用: 人, 大鼠 WB, IHC (p), FACS 宿主: 兔 Polyclonal RB01477 unconjugated
anti-Discoidin Domain Receptor tyrosine Kinase 1 (DDR1) (AA 341-909) antibodyDDR1 适用: 人, 大鼠, 小鼠 WB, ELISA, IHC, FACS, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Discoidin Domain Receptor tyrosine Kinase 1 (DDR1) (AA 299-330) antibodyDDR1 适用: 人 WB, ELISA, IHC, FACS, IF 宿主: 兔 Polyclonal unconjugated
anti-Discoidin Domain Receptor tyrosine Kinase 1 (DDR1) (AA 568-829) antibodyDDR1 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Discoidin Domain Receptor tyrosine Kinase 1 (DDR1) (AA 21-176) antibodyDDR1 适用: 人 ELISA, FACS 宿主: 小鼠 Monoclonal 4F2C12 unconjugated
anti-Discoidin Domain Receptor tyrosine Kinase 1 (DDR1) (AA 17-47) antibodyDDR1 适用: 人, 大鼠 WB, ELISA, IHC, FACS 宿主: 兔 Polyclonal unconjugated
anti-Discoidin Domain Receptor tyrosine Kinase 1 (DDR1) antibodyDDR1 适用: 人 WB, IHC (p) 宿主: 小鼠 Monoclonal 4C4 unconjugated
anti-Discoidin Domain Receptor tyrosine Kinase 1 (DDR1) (AA 21-120) antibodyDDR1 适用: 大鼠, 小鼠 WB, ELISA, IHC (p), IF (p), IF (cc), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Discoidin Domain Receptor tyrosine Kinase 1 (DDR1) (AA 396-430) antibodyDDR1 适用: 人, 小鼠 WB 宿主: 兔 Polyclonal RB50593 unconjugated
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应用备注
- Optimal dilution of the DDR1 antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Lyophilized
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缓冲液
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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储存条件
- 4 °C,-20 °C
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储存方法
- After reconstitution, the DDR1 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
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- DDR1 (Discoidin Domain Receptor tyrosine Kinase 1 (DDR1))
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别名
- DDR1
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背景
- DDR1 (Discoidin domain receptor family, member 1) also known as NEP, EDDR1, NTRK4, TRKE, DDR, CAK or RTK6, is a human gene. The protein encoded by this gene is a RTK that is widely expressed in normal and transformed epithelial cells and is activated by various types of collagen. This protein belongs to a subfamily of tyrosine kinase receptors with a homology region to the Dictyostelium discoideum protein discoidin I in their extracellular domain. The DDR1 gene is mapped on 6p21.33. The fibrillar collagens and immobilized collagen activated DDR1 receptor phosphorylation after prolonged treatment. Bhatt et al. (2000) showed thatDdr1was highly expressed in the cerebellum of developing and adult mouse brain, and that bothDdr1and collagen IV were highly expressed in the pial layer of the cerebellar cortex cocultures of collagen I- and IV-expressing mouse pial cells withDdr1-expressing granule cells resulted in granule cell neurite extension. Inhibition of collagen-Ddr1signaling reduced granule cell neurite elongation.
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UniProt
- Q08345
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途径
- RTK signaling, Smooth Muscle Cell Migration
抗原
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