MAP2K6 抗体 (pSer207) (Cy3)
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- 抗原 See all MAP2K6 抗体
- MAP2K6 (Mitogen-Activated Protein Kinase Kinase 6 (MAP2K6))
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抗原表位
- pSer207
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适用
- 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This MAP2K6 antibody is conjugated to Cy3
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应用范围
- Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
- 交叉反应
- 小鼠, 大鼠
- 预测反应
- Human
- 纯化方法
- Purified by Protein A.
- 免疫原
- KLH conjugated synthetic phosphopeptide derived from human MEK6 around the phosphorylation site of Ser207
- 亚型
- IgG
- Top Product
- Discover our top product MAP2K6 Primary Antibody
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- 应用备注
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IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 μg/μL
- 缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- 有效期
- 12 months
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- 抗原
- MAP2K6 (Mitogen-Activated Protein Kinase Kinase 6 (MAP2K6))
- 别名
- MEK6 (MAP2K6 产品)
- 背景
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Synonyms: MAP kinase kinase 6, MAPK/ERK kinase 6, MAPKK6, MEK6, Mitogen Activated Protein Kinase Kinase 6, MKK 6, MKK6, PRKMK6, SAPKK3, Dual specicity mitogen activated protein kinase kinase 6, MKK 6, Dual specicity mitogen activated protein kinase kinase 6, EC 2.7.12.2, MP2K6_HUMAN.
Background: Mitogen activated protein kinase kinase 6 (MEK6 or MKK6) belongs to the serine/threonine protein kinase family and the MAPK kinase subfamily (MAP2K, MKK or MEKs). MEK6, closely related to MEK3, catalyzes the concomitant phosphorylation of a threonine and a tyrosine residue in MAP kinase p38, thus activating it, in response to inflammatory cytokines and environmental stress.As an essential component of p38 MAP kinase mediated signal transduction pathway, this protein is involved in many cellular processes such as stress induced cell cycle arrest, transcription activation and apoptosis.
- 基因ID
- 5608
- 途径
- MAPK Pathway, TLR signaling, Activation of Innate immune Response, Regulation of Muscle Cell Differentiation, Toll-Like Receptors Cascades
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