Fgr 抗体 (AA 3-33)
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Quick Overview for Fgr 抗体 (AA 3-33) (ABIN7873536)
抗原
See all Fgr (FGR) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 3-33
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原理
- FGR Antibody / c-FGR proto oncogene
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纯化方法
- SAS precipitation
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免疫原
- A portion of amino acids 3-33 from the human protein was used as the immunogen for the FGR antibody.
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亚型
- Ig Fraction
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应用备注
- The stated application concentrations are suggested starting points. Titration of the FGR antibody may be required due to differences in protocols and secondary/substrate sensitivity.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- In 1X PBS, pH 7.4, with 0.09 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Aliquot the FGR antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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- Fgr (FGR) (Gardner-Rasheed Feline Sarcoma Viral (V-Fgr) Oncogene Homolog (FGR))
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别名
- FGR
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背景
- FGR is a member of the Src family of protein tyrosine kinases (PTKs). This protein contains N-terminal sites for myristylation and palmitylation, a PTK domain, and SH2 and SH3 domains which are involved in mediating protein-protein interactions with phosphotyrosine-containing and proline-rich motifs, respectively. It localizes to plasma membrane ruffles, and functions as a negative regulator of cell migration and adhesion triggered by the beta-2 integrin signal transduction pathway. Infection with Epstein-Barr virus results in the overexpression of this protein.
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UniProt
- P09769
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途径
- Sensory Perception of Sound, Stem Cell Maintenance, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, CXCR4-mediated Signaling Events, Thromboxane A2 Receptor Signaling
抗原
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