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Fgr 抗体 (N-Term)

Name: Fgr 抗体 (N-Term)
SKU: ABIN392096
Availability: OutOfStock

FGR 适用: 人 WB, IHC (p), IF 宿主: 兔 Polyclonal RB3095 unconjugated

Anti-FGR Antibody (N-term) at 1:1000 dilution + Raji whole cell lysate Lysates/proteins at 20 μg per lane.

Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by AEC staining.

IHC (p)

Western blot analysis of FGR (arrow) using FGR Antibody (N-term) (ABIN392096 and ABIN2841848).

Confocal immunofluorescent analysis of FGR Antibody (N-term) (ABIN392096 and ABIN2841848) with MDA-M cell followed by Alexa Fluor 488-conjugated goat anti-rabbit lgG (green).

Anti-FGR Antibody (N-term) at 1:2000 dilution + Raji whole cell lysate Lysates/proteins at 20 μg per lane.

5 images

(2 references)

产品编号 ABIN392096

发货至: 中国

Datasheet as PDF

抗原 See all Fgr (FGR) 抗体

Fgr (FGR) (Gardner-Rasheed Feline Sarcoma Viral (V-Fgr) Oncogene Homolog (FGR))
抗原表位
15

7

7

5

4

4

3

2

2

2

1

1

1

1

1

1

1

1

1

1
AA 3-33, N-Term
适用
68

18

10

2

1

1

1

1

1
人
宿主
64

4

3
兔
Compatible Secondaries
克隆类型
68

2
多克隆
标记
33

5

5

3

3

3

3

3

3

3

1

1

1

1

1

1

1
This Fgr antibody is un-conjugated
应用范围
37

30

18

13

13

9

5

4

3

3

2
Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)

纯化方法

This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

免疫原

This FGR antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 3-33 amino acids from the N-terminal region of human FGR.

克隆位点

RB3095

亚型

Ig Fraction

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anti-Gardner-Rasheed Feline Sarcoma Viral (V-Fgr) Oncogene Homolog (FGR) (AA 11-72) antibody
FGR 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated

anti-Gardner-Rasheed Feline Sarcoma Viral (V-Fgr) Oncogene Homolog (FGR) antibody
FGR 适用: 人, 小鼠 WB, ELISA, IHC 宿主: 小鼠 Monoclonal 6G2 unconjugated

anti-Gardner-Rasheed Feline Sarcoma Viral (V-Fgr) Oncogene Homolog (FGR) (AA 11-40), (N-Term) antibody
FGR 适用: 人 WB, IHC (p), IF, EIA 宿主: 兔 Polyclonal unconjugated

anti-Gardner-Rasheed Feline Sarcoma Viral (V-Fgr) Oncogene Homolog (FGR) (AA 1-529) antibody
FGR 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated

anti-Gardner-Rasheed Feline Sarcoma Viral (V-Fgr) Oncogene Homolog (FGR) (AA 1-529) antibody
FGR 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated

anti-Gardner-Rasheed Feline Sarcoma Viral (V-Fgr) Oncogene Homolog (FGR) (Internal Region) antibody
FGR 适用: 人, 小鼠, 大鼠 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated

anti-Gardner-Rasheed Feline Sarcoma Viral (V-Fgr) Oncogene Homolog (FGR) (C-Term) antibody
Verified FGR 适用: 人 WB, ELISA 宿主: 山羊 Polyclonal unconjugated

anti-Gardner-Rasheed Feline Sarcoma Viral (V-Fgr) Oncogene Homolog (FGR) (AA 1-100) antibody
FGR 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated

anti-Gardner-Rasheed Feline Sarcoma Viral (V-Fgr) Oncogene Homolog (FGR) antibody
FGR 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated

应用备注

IF: 1:10~50. WB: 1:1000. WB: 1:2000. WB: 1:1000. IHC-P: 1:50~100

限制

仅限研究用
状态

Liquid

缓冲液

Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

储存条件

4 °C,-20 °C

储存方法

Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

有效期

6 months
Henderson, Gonzales, Arora, Choudhary, Trent, Von Hoff, Mousses, Azorsa: "High-throughput RNAi screening identifies a role for TNK1 in growth and survival of pancreatic cancer cells." in: Molecular cancer research : MCR, Vol. 9, Issue 6, pp. 724-32, (2011) (PubMed).

Tatarov, Mitchell, Seywright, Leung, Brunton, Edwards: "SRC family kinase activity is up-regulated in hormone-refractory prostate cancer." in: Clinical cancer research : an official journal of the American Association for Cancer Research, Vol. 15, Issue 10, pp. 3540-9, (2009) (PubMed).
抗原

Fgr (FGR) (Gardner-Rasheed Feline Sarcoma Viral (V-Fgr) Oncogene Homolog (FGR))

别名

FGR (FGR 产品)

别名

SRC2 antibody, c-fgr antibody, c-src2 antibody, p55-Fgr antibody, p55c-fgr antibody, p58-Fgr antibody, p58c-fgr antibody, FGR proto-oncogene, Src family tyrosine kinase antibody, FGR antibody, Fgr antibody

背景

FGR is a member of the Src family of protein tyrosine kinases (PTKs). This protein contains N-terminal sites for myristylation and palmitylation, a PTK domain, and SH2 and SH3 domains which are involved in mediating protein-protein interactions with phosphotyrosine-containing and proline-rich motifs, respectively. It localizes to plasma membrane ruffles, and functions as a negative regulator of cell migration and adhesion triggered by the beta-2 integrin signal transduction pathway. Infection with Epstein-Barr virus results in the overexpression of this protein.

分子量

59479

基因ID

2268

NCBI登录号

NP_001036194, NP_001036212, NP_005239

UniProt

P09769

途径

Sensory Perception of Sound, Stem Cell Maintenance, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, CXCR4-mediated Signaling Events, Thromboxane A2 Receptor Signaling