ATG4D 抗体 (AA 220-249)
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北京 101111
Quick Overview for ATG4D 抗体 (AA 220-249) (ABIN7872340)
抗原
See all ATG4D 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 220-249
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原理
- ATG4D Antibody
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纯化方法
- Purified
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免疫原
- A portion of amino acids 220-249 from the human protein was used as the immunogen for the ATG4D antibody.
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亚型
- Ig Fraction
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anti-Autophagy related 4D Cysteine Peptidase (ATG4D) (AA 441-470), (C-Term) antibody
ATG4D 适用: 人 WB, IF, IHC (p) 宿主: 兔 Polyclonal RB7567 unconjugated
anti-Autophagy related 4D Cysteine Peptidase (ATG4D) (AA 14-43), (N-Term) antibodyATG4D 适用: 人, 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal RB7563 unconjugated
anti-Autophagy related 4D Cysteine Peptidase (ATG4D) (AA 14-43) antibodyATG4D 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Autophagy related 4D Cysteine Peptidase (ATG4D) (AA 220-249) antibodyATG4D 适用: 人, 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal RB7565 unconjugated
anti-Autophagy related 4D Cysteine Peptidase (ATG4D) (AA 381-474) antibodyATG4D 适用: 小鼠 WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Autophagy related 4D Cysteine Peptidase (ATG4D) (C-Term) antibodyATG4D 适用: 人, 小鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Autophagy related 4D Cysteine Peptidase (ATG4D) (AA 42-71), (N-Term) antibodyATG4D 适用: 小鼠 WB, IF, IHC (p) 宿主: 兔 Polyclonal RB14788 unconjugated
anti-Autophagy related 4D Cysteine Peptidase (ATG4D) (AA 227-257) antibodyATG4D 适用: 人, 小鼠 WB, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
anti-Autophagy related 4D Cysteine Peptidase (ATG4D) (AA 326-356) antibodyATG4D 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB11866 unconjugated
anti-Autophagy related 4D Cysteine Peptidase (ATG4D) (Center) antibodyATG4D 适用: 人, 小鼠 IHC (p) 宿主: 兔 Polyclonal unconjugated
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应用备注
- The stated application concentrations are suggested starting points. Titration of the ATG4D antibody may be required due to differences in protocols and secondary/substrate sensitivity.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- In 1X PBS, pH 7.4, with 0.09 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Aliquot the ATG4D antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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- ATG4D (Autophagy related 4D Cysteine Peptidase (ATG4D))
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别名
- ATG4D
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背景
- Macroautophagy is the major inducible pathway for the general turnover of cytoplasmic constituents in eukaryotic cells, it is also responsible for the degradation of active cytoplasmic enzymes and organelles during nutrient starvation. Macroautophagy involves the formation of double-membrane bound autophagosomes which enclose the cytoplasmic constituent targeted for degradation in a membrane bound structure, which then fuse with the lysosome (or vacuole) releasing a single-membrane bound autophagic bodies which are then degraded within the lysosome (or vacuole). APG4 is a cysteine protease required for autophagy, which cleaves the C-terminal part of either MAP1LC3, GABARAPL2 or GABARAP, allowing the liberation of form I. A subpopulation of form I is subsequently converted to a smaller form (form II). Form II, with a revealed C-terminal glycine, is considered to be the phosphatidylethanolamine (PE)-conjugated form, and has the capacity for the binding to autophagosomes.
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UniProt
- Q86TL0
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途径
- Autophagy
抗原
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