Neuregulin 1 抗体 (AA 21-242)
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Quick Overview for Neuregulin 1 抗体 (AA 21-242) (ABIN7872153)
抗原
See all Neuregulin 1 (NRG1) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 21-242
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原理
- NRG1 Antibody / Neuregulin-1
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纯化方法
- Protein G affinity chromatography
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免疫原
- A recombinant human partial protein (amino acids 21-242) was used as the immunogen for the NRG1 antibody.
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亚型
- IgG1, kappa
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应用备注
- Optimal dilution of the NRG1 antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.2 mg/mL
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缓冲液
- 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store the NRG1 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
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- Neuregulin 1 (NRG1)
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别名
- NRG1
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背景
- Neuregulin-1, also called Heregulin-1, is a membrane glycoprotein that mediates cell-cell signaling and plays a critical role in the growth and development of multiple organ systems. An extraordinary variety of different isoforms are produced from this gene through alternative promoter usage and splicing. These isoforms are expressed in a tissue-specific manner and differ significantly in their structure, and are classified as types I, II, III, IV, V and VI. Dysregulation of this gene has been linked to diseases such as cancer, schizophrenia, and bipolar disorder (BPD).
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UniProt
- Q02297
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途径
- RTK signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Regulation of Muscle Cell Differentiation
抗原
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