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Neuregulin 1 抗体 (AA 21-242)

The 小鼠 单克隆 anti-Neuregulin 1 antibody is suitable to detect Neuregulin 1 in samples from 人. It has been validated for IHC (p).
产品编号 ABIN7872153
发货至: 中国
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Quick Overview for Neuregulin 1 抗体 (AA 21-242) (ABIN7872153)

抗原

See all Neuregulin 1 (NRG1) 抗体
Neuregulin 1 (NRG1)

适用

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宿主

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小鼠

克隆类型

  • 119
  • 21
单克隆

标记

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This Neuregulin 1 antibody is un-conjugated

应用范围

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Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

克隆位点

HRGA1-1
  • 抗原表位

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    AA 21-242

    原理

    NRG1 Antibody / Neuregulin-1

    纯化方法

    Protein G affinity chromatography

    免疫原

    A recombinant human partial protein (amino acids 21-242) was used as the immunogen for the NRG1 antibody.

    亚型

    IgG1, kappa
  • 应用备注

    Optimal dilution of the NRG1 antibody should be determined by the researcher.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.2 mg/mL

    缓冲液

    0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05 % sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store the NRG1 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
  • 抗原

    Neuregulin 1 (NRG1)

    别名

    NRG1

    背景

    Neuregulin-1, also called Heregulin-1, is a membrane glycoprotein that mediates cell-cell signaling and plays a critical role in the growth and development of multiple organ systems. An extraordinary variety of different isoforms are produced from this gene through alternative promoter usage and splicing. These isoforms are expressed in a tissue-specific manner and differ significantly in their structure, and are classified as types I, II, III, IV, V and VI. Dysregulation of this gene has been linked to diseases such as cancer, schizophrenia, and bipolar disorder (BPD).

    UniProt

    Q02297

    途径

    RTK signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Regulation of Muscle Cell Differentiation
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