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CFHR5 抗体 (AA 203-231)

The 兔 多克隆 anti-CFHR5 antibody (ABIN7872079) specifically detects CFHR5 in WB, FACS 和 IHC (p). The antibody is reactive with 人 samples.
产品编号 ABIN7872079
发货至: 中国
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Quick Overview for CFHR5 抗体 (AA 203-231) (ABIN7872079)

抗原

See all CFHR5 抗体
CFHR5 (Complement Factor H-Related 5 (CFHR5))

适用

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宿主

  • 22
  • 13

克隆类型

  • 23
  • 12
多克隆

标记

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  • 1
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This CFHR5 antibody is un-conjugated

应用范围

  • 24
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  • 4
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Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
  • 抗原表位

    • 7
    • 4
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    • 2
    • 1
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    AA 203-231

    原理

    FHR-5 Antibody / Complement factor H-related protein 5 / CFHR5

    纯化方法

    Antigen affinity purified

    免疫原

    A portion of amino acids 203-231 from the human protein was used as the immunogen for the FHR-5 antibody.

    亚型

    Ig Fraction
  • 应用备注

    The stated application concentrations are suggested starting points. Titration of the FHR-5 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    In 1X PBS, pH 7.4, with 0.09 % sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Aliquot the FHR-5 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
  • 抗原

    CFHR5 (Complement Factor H-Related 5 (CFHR5))

    别名

    FHR-5

    背景

    CFHR5 / FHR-5 is a member of a small complement factor H (CFH) gene cluster on chromosome 1. Each member of this gene family contains multiple short consensus repeats (SCRs) typical of regulators of complement activation. The protein encoded by this gene has nine SCRs with the first two repeats having heparin binding properties, a region within repeats 5-7 having heparin binding and C reactive protein binding properties, and the C-terminal repeats being similar to a complement component 3 b (C3b) binding domain. This protein co-localizes with C3, binds C3b in a dose-dependent manner, and is recruited to tissues damaged by C-reactive protein. Allelic variations in this gene have been associated, but not causally linked, with two different forms of kidney disease: membranoproliferative glomerulonephritis type II (MPGNII) and hemolytic uraemic syndrome (HUS). [provided by RefSeq].

    UniProt

    Q9BXR6
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