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TDG 抗体 (AA 15-370)

The 兔 多克隆 anti-TDG antibody (ABIN7870789) specifically detects TDG in WB, ELISA, IF 和 FACS. The antibody is reactive with 人, 小鼠 和 大鼠 samples.
产品编号 ABIN7870789
发货至: 中国
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Quick Overview for TDG 抗体 (AA 15-370) (ABIN7870789)

抗原

See all TDG 抗体
TDG (Thymine-DNA Glycosylase (TDG))

适用

  • 51
  • 19
  • 11
  • 2
  • 1
人, 小鼠, 大鼠

宿主

  • 39
  • 12

克隆类型

  • 42
  • 10
多克隆

标记

  • 45
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This TDG antibody is un-conjugated

应用范围

  • 41
  • 15
  • 12
  • 11
  • 6
  • 5
  • 4
  • 3
  • 2
  • 1
  • 1
Western Blotting (WB), ELISA, Immunofluorescence (IF), Flow Cytometry (FACS)
  • 抗原表位

    • 6
    • 5
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 15-370

    原理

    TDG Antibody / Thymine-DNA glycosylase

    纯化方法

    Antigen affinity purified

    免疫原

    E. coli-derived recombinant human protein (amino acids Q15-R370) was used as the immunogen for the TDG antibody.

    亚型

    IgG
  • 应用备注

    Optimal dilution of the TDG antibody should be determined by the researcher.

    限制

    仅限研究用
  • 状态

    Lyophilized

    缓冲液

    0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

    储存条件

    4 °C,-20 °C

    储存方法

    After reconstitution, the TDG antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
  • 抗原

    TDG (Thymine-DNA Glycosylase (TDG))

    别名

    TDG

    背景

    G/T mismatch-specific thymine DNA glycosylase is an enzyme that in humans is encoded by the TDG gene. The protein encoded by this gene belongs to the TDG/mug DNA glycosylase family. Thymine-DNA glycosylase (TDG) removes thymine moieties from G/T mismatches by hydrolyzing the carbon-nitrogen bond between the sugar-phosphate backbone of DNA and the mispaired thymine. With lower activity, this enzyme also removes thymine from C/T and T/T mispairings. TDG can also remove uracil and 5-bromouracil from mispairings with guanine. This enzyme plays a central role in cellular defense against genetic mutation caused by the spontaneous deamination of 5-methylcytosine and cytosine. This gene may have a pseudogene in the p arm of chromosome 12.

    UniProt

    Q13569

    途径

    DNA Damage Repair, Chromatin Binding
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