LEF1 抗体 (AA 14-274)
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Quick Overview for LEF1 抗体 (AA 14-274) (ABIN7870624)
抗原
See all LEF1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 14-274
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原理
- TCF1 alpha Antibody / LEF1 / Lymphoid enhancer-binding factor 1
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纯化方法
- Affinity purified
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免疫原
- An E. coli-derived human protein (amino acids D14-H274) was used as the immunogen for the TCF1 alpha antibody.
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亚型
- IgG
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应用备注
- Optimal dilution of the TCF1 alpha antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Lyophilized
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缓冲液
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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储存条件
- 4 °C,-20 °C
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储存方法
- After reconstitution, the TCF1 alpha antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
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- LEF1 (Lymphoid Enhancer-Binding Factor 1 (LEF1))
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别名
- TCF1 alpha
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背景
- Lymphoid enhancer-binding factor 1 (LEF1), also called T cell-specific transcription factor 1-alpha (TCF1 alpha) is a protein that in humans is encoded by the LEF1 gene. This gene encodes a transcription factor belonging to a family of proteins that share homology with the high mobility group protein-1. The protein encoded by this gene can bind to a functionally important site in the T-cell receptor-alpha enhancer, thereby conferring maximal enhancer activity. This transcription factor is involved in the Wnt signaling pathway, and it may function in hair cell differentiation and follicle morphogenesis. Mutations in this gene have been found in somatic sebaceous tumors. This gene has also been linked to other cancers, including androgen-independent prostate cancer. Alternative splicing results in multiple transcript variants.
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UniProt
- Q9UJU2
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途径
- WNT signaling, Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Hormone Metabolic Process, Nuclear Hormone Receptor Binding, Chromatin Binding
抗原
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