IL1A 抗体 (AA 113-271)
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北京 101111
Quick Overview for IL1A 抗体 (AA 113-271) (ABIN7870147)
抗原
See all IL1A 抗体适用
宿主
克隆类型
标记
应用范围
质量等级
克隆位点
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抗原表位
- AA 113-271
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原理
- IL-1 alpha Antibody / IL1A (azide and preservative free)
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纯化方法
- Protein G affinity chromatography
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免疫原
- A portion of amino acids 113-271 from the human protein was used as the immunogen for the IL-1 alpha antibody.
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亚型
- IgG2b, kappa
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anti-Interleukin 1 alpha (IL1A) (AA 177-206) antibody
IL1A 适用: 人 WB, FACS, IHC (p) 宿主: 兔 Polyclonal RB21521 unconjugated
anti-Interleukin 1 alpha (IL1A) (AA 172-271) antibodyIL1A 适用: 人 WB, IP, ELISA, IF 宿主: 小鼠 Monoclonal 4F9 unconjugated
anti-Interleukin 1 alpha (IL1A) antibodyIL1A 适用: 人 ELISA, FACS 宿主: 小鼠 Monoclonal 6G4A5 unconjugated
anti-Interleukin 1 alpha (IL1A) (AA 113-271) antibodyIL1A 适用: 人 WB 宿主: 小鼠 Monoclonal 3# unconjugated
anti-Interleukin 1 alpha (IL1A) (AA 90-268) antibodyIL1A 适用: 山羊 WB, IHC, IP, ICC 宿主: 小鼠 Monoclonal C12 unconjugated
anti-Interleukin 1 alpha (IL1A) (AA 112-271) antibodyIL1A 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Interleukin 1 alpha (IL1A) (AA 115-270) antibodyIL1A 适用: 大鼠 WB, IHC, IP, ICC 宿主: 小鼠 Monoclonal C12 unconjugated
anti-Interleukin 1 alpha (IL1A) (N-Term) antibodyIL1A 适用: 人, 大鼠, 小鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Interleukin 1 alpha (IL1A) (AA 113-271) antibodyIL1A 适用: 人 WB, IHC 宿主: 小鼠 Monoclonal C1 unconjugated
anti-Interleukin 1 alpha (IL1A) (AA 177-206) antibodyIL1A 适用: 人 WB, IHC, ELISA, FACS 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal dilution of the IL-1 alpha antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- 1 mg/mL in 1X PBS, BSA free, sodium azide free
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储存液
- Azide free
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储存条件
- 4 °C,-20 °C
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储存方法
- Store the IL-1 alpha antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
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- IL1A (Interleukin 1 alpha (IL1A))
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别名
- IL-1 alpha
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背景
- Two forms of interleukin-1, designated IL-1 alpha and beta, have been described. Although encoded by distinct genes and exhibiting roughly only 25 % sequence identity, IL-1a and IL-1b bind to the same receptor and seem to elicit similar biological responses. IL-1 production is generally thought to be associated with inflammation, but it has also been shown to be expressed during kidney development, thymocyte differentiation and cartilage degradation. IL-1 plays a critical role in the regulation of immune response and inflammation, acting as an activator of T and B lymphocytes and natural killer (NK) cells. In T cells, IL-1 stimulates the production of IL-2 and selectively inhibits IL-4 expression. IL-1 induces B cell proliferation and maturation, and immunoglobulin synthesis. NK cells require IL-1 for production of the anti-pathogen IFN-. IL-1 has also been implicated in several pathological conditions including rheumatoid arthritis, inflammatory bowel disease and atherosclerosis.
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UniProt
- P01583
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途径
- NF-kappaB Signaling, Autophagy, Cancer Immune Checkpoints
抗原
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