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PPARG 抗体 (AA 1-512)

Name: PPARG 抗体 (AA 1-512)
SKU: ABIN7869446
Availability: OutOfStock

This 兔多克隆 antibody specifically detects PPARG in WB. It exhibits reactivity toward 斑马鱼.

产品编号 ABIN7869446

发货至: 中国

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Quick Overview for PPARG 抗体 (AA 1-512) (ABIN7869446)

抗原

See all PPARG 抗体

PPARG (Peroxisome Proliferator-Activated Receptor gamma (PPARG))

适用

斑马鱼

宿主

兔

克隆类型

多克隆

标记

This PPARG antibody is un-conjugated

应用范围

Western Blotting (WB)

Discover our top product PPARG Primary Antibody

抗原表位
27

17

16

16

16

12

10

5

5

4

4

3

3

3

3

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
AA 1-512

原理

Zebrafish Ppar gamma Antibody / Pparg

纯化方法

Antigen affinity chromatography

免疫原

E. coli-derived zebrafish Ppar gamma recombinant protein (amino acids M1-D512) was used as the immunogen for the Zebrafish Ppar gamma antibody.

亚型

Ig Fraction
anti-Peroxisome Proliferator-Activated Receptor gamma (PPARG) (AA 315-420) antibody
PPARG 适用: 人, 小鼠, 大鼠, 山羊 WB, ELISA, FACS, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated

anti-Peroxisome Proliferator-Activated Receptor gamma (PPARG) (AA 101-200) antibody
PPARG 适用: 人, 小鼠, 大鼠, Cow, 绵羊 WB, ELISA, FACS, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated

anti-Peroxisome Proliferator-Activated Receptor gamma (PPARG) (pSer112) antibody
PPARG 适用: 人, 小鼠, 大鼠, 犬 WB, ELISA, FACS, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated

anti-Peroxisome Proliferator-Activated Receptor gamma (PPARG) (AA 149-273) antibody
PPARG 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

anti-Peroxisome Proliferator-Activated Receptor gamma (PPARG) (pSer112) antibody
PPARG 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, ICC, IF 宿主: 兔 Polyclonal unconjugated

anti-Peroxisome Proliferator-Activated Receptor gamma (PPARG) (pSer273) antibody
PPARG 适用: 人, 小鼠, 大鼠, 绵羊, 豚鼠 WB, ELISA, ICC, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated

anti-Peroxisome Proliferator-Activated Receptor gamma (PPARG) antibody
PPARG 适用: 人 WB, IHC, ELISA, IF 宿主: 小鼠 Monoclonal 8D1H8F4 unconjugated

anti-Peroxisome Proliferator-Activated Receptor gamma (PPARG) (AA 1-30), (N-Term) antibody
PPARG 适用: 人 WB, FACS 宿主: 兔 Polyclonal RB22139 unconjugated

anti-Peroxisome Proliferator-Activated Receptor gamma (PPARG) (AA 311-493) antibody
PPARG 适用: 大鼠 WB, IHC 宿主: 小鼠 Monoclonal C5 unconjugated

anti-Peroxisome Proliferator-Activated Receptor gamma (PPARG) (AA 349-488) antibody
PPARG 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

应用备注

Optimal dilution of the Zebrafish Ppar gamma antibody should be determined by the researcher.

限制

仅限研究用
状态

Lyophilized

缓冲液

0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

储存条件

4 °C,-20 °C

储存方法

After reconstitution, the Zebrafish Ppar gamma antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
抗原

PPARG (Peroxisome Proliferator-Activated Receptor gamma (PPARG))

别名

Ppar gamma

背景

Pparg (Peroxisome proliferator-activated receptor gamma) is a critical transcription factor that belongs to the nuclear receptor superfamily. It plays a vital role in regulating lipid metabolism, glucose homeostasis, inflammation, and adipocyte differentiation. As a ligand-activated transcription factor, Pparg regulates the expression of genes involved in a variety of physiological processes, including energy metabolism, insulin sensitivity, and immune response. Pparg is activated by fatty acids and other lipid metabolites, making it a key regulator of metabolic homeostasis.
In zebrafish, Pparg is an ortholog of the human PPARG gene. The zebrafish and human proteins share a high degree of sequence conservation, particularly in their DNA binding domain and ligand-binding domain, which are essential for their function as transcription factors. This evolutionary conservation suggests that the role of Pparg in regulating lipid metabolism and adipogenesis is preserved across species, making zebrafish a valuable model for studying the molecular mechanisms of metabolic diseases and obesity.
Pparg in zebrafish has isoforms, which may exhibit tissue-specific expression and functional variation. The existence of isoforms allows for regulation of different target genes depending on developmental stages, tissue types, and environmental conditions. These isoforms may also be involved in regulating distinct physiological processes, such as fatty acid metabolism, inflammatory response, and immune cell differentiation.
In zebrafish, Pparg is expressed in various tissues, including the adipose tissue, liver, and muscles, as well as in developing embryos. Its expression is tightly regulated to ensure proper energy homeostasis and organ development. Pparg plays an essential role in early development, especially in regulating the formation of adipocytes (fat cells), which are important for long-term energy storage and regulation. Disruption of Pparg function in zebrafish can result in defects in lipid metabolism and adipogenesis, providing a model for studying metabolic disorders.

UniProt

A6XMH6

途径

MAPK Pathway, Nuclear Receptor Transcription Pathway, Steroid Hormone Mediated Signaling Pathway, Negative Regulation of Hormone Secretion, Carbohydrate Homeostasis, Regulation of Lipid Metabolism by PPARalpha, Positive Regulation of Endopeptidase Activity, Brown Fat Cell Differentiation, Positive Regulation of fat Cell Differentiation